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    PARK7 Parkinson disease (autosomal recessive, early onset) 7 [ Gallus gallus (chicken) ]

    Gene ID: 395277, updated on 5-Aug-2018

    Summary

    Symbol
    PARK7provided by CGNC
    Full Name
    Parkinson disease (autosomal recessive, early onset) 7provided by CGNC
    Primary source
    CGNC:66200
    See related
    Ensembl:ENSGALG00000036214
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    DJ-1
    Orthologs

    Genomic context

    See PARK7 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 21 NC_006108.5 (264288..272660, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 21 NC_006108.4 (245683..254055, complement)

    Chromosome 21 - NC_006108.5Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene solute carrier family 45, member 1 Neighboring gene uncharacterized LOC107054907 Neighboring gene ERBB receptor feedback inhibitor 1 Neighboring gene uncharacterized LOC107054906 Neighboring gene tumor necrosis factor receptor superfamily member 9 Neighboring gene urotensin 2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein deglycase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    DNA repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    adult locomotory behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hydrogen peroxide ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cellular response to oxidative stress ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    dopamine uptake involved in synaptic transmission ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    glucose homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    guanine deglycation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    guanine deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    guanine deglycation, glyoxal removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    guanine deglycation, methylglyoxal removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    insulin secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    NOT methylglyoxal metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of cell death ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of reactive oxygen species biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of NAD(P)H oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of acute inflammatory response to antigenic stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of oxidative phosphorylation uncoupler activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NOT protein deglycation, methylglyoxal removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein deglycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    NOT protein deglycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of neuron apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to hydrogen peroxide ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    single fertilization IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic transmission, dopaminergic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane raft IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    presynapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein/nucleic acid deglycase DJ-1
    Names
    Parkinson disease 7
    maillard deglycase
    parkinson disease protein 7 homolog
    parkinsonism-associated deglycase
    protein DJ-1
    protein deglycase DJ-1
    NP_989916.1
    XP_015152305.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204585.1NP_989916.1  protein/nucleic acid deglycase DJ-1

      See identical proteins and their annotated locations for NP_989916.1

      Status: PROVISIONAL

      Source sequence(s)
      AB076264
      UniProtKB/Swiss-Prot
      Q8UW59
      Conserved Domains (2) summary
      cd03135
      Location:6172
      GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
      TIGR01383
      Location:5184
      not_thiJ; DJ-1 family protein

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006108.5 Reference GRCg6a Primary Assembly

      Range
      264288..272660 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015296819.2XP_015152305.1  protein/nucleic acid deglycase DJ-1 isoform X1

      UniProtKB/TrEMBL
      D5M8S2
      Related
      ENSGALP00000060130.1
      Conserved Domains (1) summary
      TIGR01383
      Location:5184
      not_thiJ; DJ-1 family protein
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