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    Map4 microtubule-associated protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367171, updated on 12-Aug-2018

    Summary

    Official Symbol
    Map4provided by RGD
    Official Full Name
    microtubule-associated protein 4provided by RGD
    Primary source
    RGD:1564359
    See related
    Ensembl:ENSRNOG00000020748
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mtap4
    Expression
    Biased expression in Muscle (RPKM 577.6), Heart (RPKM 378.1) and 9 other tissues See more
    Orthologs

    Genomic context

    See Map4 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (118013584..118159934)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (117366074..117515388)

    Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene cathelicidin antimicrobial peptide Neighboring gene cell division cycle 25A Neighboring gene DExH-box helicase 30 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    tubulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell division ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of spindle orientation ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule sliding ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle organization ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axoneme ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    microtubule-associated protein 4
    Names
    MAP-4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024278.1NP_001019449.1  microtubule-associated protein 4

      See identical proteins and their annotated locations for NP_001019449.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088405
      UniProtKB/Swiss-Prot
      Q5M7W5
      Related
      ENSRNOP00000053011.4, ENSRNOT00000056166.4
      Conserved Domains (1) summary
      pfam00418
      Location:928957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

      Range
      118013584..118159934
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006243820.3XP_006243882.1  microtubule-associated protein 4 isoform X8

      Conserved Domains (1) summary
      pfam00418
      Location:19681997
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    2. XM_006243818.3XP_006243880.1  microtubule-associated protein 4 isoform X6

      Conserved Domains (1) summary
      pfam00418
      Location:20042033
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    3. XM_006243819.3XP_006243881.1  microtubule-associated protein 4 isoform X7

      Conserved Domains (1) summary
      pfam00418
      Location:20042033
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    4. XM_006243813.3XP_006243875.1  microtubule-associated protein 4 isoform X1

      Conserved Domains (1) summary
      pfam00418
      Location:20422071
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    5. XM_006243815.3XP_006243877.1  microtubule-associated protein 4 isoform X3

      Conserved Domains (1) summary
      pfam00418
      Location:20422071
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    6. XM_006243814.3XP_006243876.1  microtubule-associated protein 4 isoform X2

      Conserved Domains (1) summary
      pfam00418
      Location:20422071
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    7. XM_006243816.3XP_006243878.1  microtubule-associated protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A0G2JW88
      Related
      ENSRNOP00000069786.1, ENSRNOT00000056161.4
      Conserved Domains (1) summary
      pfam00418
      Location:20422071
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    8. XM_017595795.1XP_017451284.1  microtubule-associated protein 4 isoform X5

    9. XM_006243824.3XP_006243886.1  microtubule-associated protein 4 isoform X14

    10. XM_006243825.3XP_006243887.1  microtubule-associated protein 4 isoform X15

    11. XM_006243821.3XP_006243883.1  microtubule-associated protein 4 isoform X9

      Conserved Domains (1) summary
      pfam00418
      Location:966995
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    12. XM_006243823.3XP_006243885.1  microtubule-associated protein 4 isoform X11

      Conserved Domains (1) summary
      pfam00418
      Location:928957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    13. XM_006243822.3XP_006243884.1  microtubule-associated protein 4 isoform X10

      See identical proteins and their annotated locations for XP_006243884.1

      Conserved Domains (1) summary
      pfam00418
      Location:966995
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    14. XM_017595797.1XP_017451286.1  microtubule-associated protein 4 isoform X13

    15. XM_017595796.1XP_017451285.1  microtubule-associated protein 4 isoform X12

    Alternate Rn_Celera

    Genomic

    1. AC_000076.1 Alternate Rn_Celera

      Range
      109215219..109352108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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