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    DJ-1alpha [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36543, updated on 8-Jul-2018
    Official Symbol
    DJ-1alphaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033885
    Locus tag
    Dmel_CG6646
    Gene type
    protein coding
    RNA name
    DJ-1alpha
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6646; DJ-1; DJ-1a; DJ-1A; Dj-1alpha; Dmel\CG6646
    See DJ-1alpha in Genome Data Viewer
    Location:
    50C9-50C9; 2-68 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13942534..13943377, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9830039..9830882, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene short stop Neighboring gene Argonaute-1 Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L53 Neighboring gene Regulatory particle non-ATPase 13

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein deglycase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein deglycase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    dopamine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    guanine deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial ATP synthesis coupled electron transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron cellular homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphatidylinositol 3-kinase signaling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein deglycation, glyoxal removal IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of protein kinase B signaling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of protein kinase B signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Preferred Names
    DJ-1alpha
    Names
    CG6646-PA
    DJ-1A
    DJ-1alpha-PA

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13942534..13943377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137072.1NP_610916.1  DJ-1alpha [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610916.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z9J4
      Related
      FBpp0086741.1, FBtr0087615
      Conserved Domains (1) summary
      cl28603
      Location:33210
      ThiJ; Putative intracellular protease/amidase [General function prediction only]
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