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    Ppme1 protein phosphatase methylesterase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361613, updated on 12-Aug-2018

    Summary

    Official Symbol
    Ppme1provided by RGD
    Official Full Name
    protein phosphatase methylesterase 1provided by RGD
    Primary source
    RGD:1309683
    See related
    Ensembl:ENSRNOG00000017227
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PME-1; RGD1309683
    Expression
    Biased expression in Brain (RPKM 214.6), Kidney (RPKM 97.2) and 9 other tissues See more
    Orthologs

    Genomic context

    See Ppme1 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (165335242..165382216, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (171535949..171582923, complement)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene phosphoglucomutase 2-like 1 Neighboring gene prolyl 4-hydroxylase subunit alpha 3 Neighboring gene C2 calcium-dependent domain containing 3 Neighboring gene uncharacterized LOC108348865 Neighboring gene uncoupling protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    protein C-terminal methylesterase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein C-terminal methylesterase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein phosphatase 2A binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphatase 2A binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase regulator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    protein demethylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein demethylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of sodium ion transport TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    protein phosphatase methylesterase 1
    NP_001178767.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191838.1NP_001178767.1  protein phosphatase methylesterase 1

      See identical proteins and their annotated locations for NP_001178767.1

      Status: PROVISIONAL

      Source sequence(s)
      AABR07071948, AC134944
      UniProtKB/Swiss-Prot
      Q4FZT2
      Related
      ENSRNOP00000023649.7, ENSRNOT00000023648.7
      Conserved Domains (3) summary
      COG0596
      Location:66370
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:78195
      Abhydrolase_5; Alpha/beta hydrolase family
      cl17036
      Location:270306
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      165335242..165382216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      152751690..152798582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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