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    chrm2a cholinergic receptor, muscarinic 2a [ Danio rerio (zebrafish) ]

    Gene ID: 352938, updated on 18-Sep-2018

    Summary

    Official Symbol
    chrm2aprovided by ZNC
    Official Full Name
    cholinergic receptor, muscarinic 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030314-1
    See related
    Ensembl:ENSDARG00000098612 Vega:OTTDARG00000032592
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    chrm2

    Genomic context

    See chrm2a in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (1146040..1285188)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (1132629..1271406)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene protein FAM180A Neighboring gene myotrophin Neighboring gene uncharacterized LOC108183355 Neighboring gene uncharacterized LOC103910364 Neighboring gene uncharacterized LOC103910365 Neighboring gene pleiotrophin Neighboring gene UPF2, regulator of nonsense mediated mRNA decay

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    G protein-coupled acetylcholine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    G protein-coupled acetylcholine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    G protein-coupled serotonin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neurotransmitter receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of heart rate IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of heart contraction IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    muscarinic acetylcholine receptor M2
    Names
    cholinergic receptor, muscarinic 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178301.1NP_840086.1  muscarinic acetylcholine receptor M2

      See identical proteins and their annotated locations for NP_840086.1

      Status: PROVISIONAL

      Source sequence(s)
      AY039653
      UniProtKB/TrEMBL
      Q801M4
      Related
      ENSDARP00000139587.1, ENSDART00000167233.2
      Conserved Domains (2) summary
      pfam00001
      Location:48231
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:40173
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      1146040..1285188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165999.4XP_005166056.1  muscarinic acetylcholine receptor M2 isoform X1

      See identical proteins and their annotated locations for XP_005166056.1

      UniProtKB/TrEMBL
      B3DKN8
      Related
      ENSDARP00000134707.1, OTTDARP00000035977, ENSDART00000166467.2
      Conserved Domains (2) summary
      pfam00001
      Location:48231
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:40173
      7tm_4; Olfactory receptor
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