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    Lpin2 lipin 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316737, updated on 13-Mar-2018
    Official Symbol
    Lpin2provided by RGD
    Official Full Name
    lipin 2provided by RGD
    Primary source
    RGD:1304588
    See related
    Ensembl:ENSRNOG00000014876
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Kidney (RPKM 124.7), Spleen (RPKM 111.6) and 9 other tissues See more
    Orthologs
    See Lpin2 in Genome Data Viewer
    Location:
    9q38
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (119517101..119591533)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (118970173..119045052)

    Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene myomesin 1 Neighboring gene uncharacterized LOC102555849 Neighboring gene tRNA-splicing endonuclease subunit Sen2-like Neighboring gene elastin microfibril interfacer 2 Neighboring gene nuclease-sensitive element-binding protein 1-like Neighboring gene structural maintenance of chromosomes flexible hinge domain containing 1

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    phosphatidate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phosphatidate phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    lipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    triglyceride biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    phosphatidate phosphatase LPIN2
    NP_001101706.1
    XP_006245724.1
    XP_006245725.1
    XP_006245726.1
    XP_006245727.1
    XP_006245728.1
    XP_017451991.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108236.1NP_001101706.1  phosphatidate phosphatase LPIN2

      See identical proteins and their annotated locations for NP_001101706.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474043
      UniProtKB/TrEMBL
      D3ZYB4
      Related
      ENSRNOP00000020476.5, ENSRNOT00000020476.7
      Conserved Domains (4) summary
      pfam15017
      Location:874894
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:1106
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:635860
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:467557
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

      Range
      119517101..119591533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245666.3XP_006245728.1  phosphatidate phosphatase LPIN2 isoform X4

      See identical proteins and their annotated locations for XP_006245728.1

      UniProtKB/TrEMBL
      D3ZYB4
      Conserved Domains (4) summary
      pfam15017
      Location:874894
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:1106
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:635860
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:467557
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
    2. XM_017596502.1XP_017451991.1  phosphatidate phosphatase LPIN2 isoform X6

    3. XM_006245665.3XP_006245727.1  phosphatidate phosphatase LPIN2 isoform X5

      Conserved Domains (4) summary
      pfam15017
      Location:861881
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:39144
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:673847
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:505595
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
    4. XM_006245663.3XP_006245725.1  phosphatidate phosphatase LPIN2 isoform X2

      Conserved Domains (4) summary
      pfam15017
      Location:911931
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:39144
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:672897
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:504594
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
    5. XM_006245662.3XP_006245724.1  phosphatidate phosphatase LPIN2 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JY62
      Related
      ENSRNOP00000070532.1, ENSRNOT00000082005.1
      Conserved Domains (4) summary
      pfam15017
      Location:912932
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:39144
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:673898
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:505595
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
    6. XM_006245664.3XP_006245726.1  phosphatidate phosphatase LPIN2 isoform X3

      Conserved Domains (4) summary
      pfam15017
      Location:882902
      AF1Q; Drug resistance and apoptosis regulator
      pfam04571
      Location:9114
      Lipin_N; lipin, N-terminal conserved region
      pfam08235
      Location:643868
      LNS2; LNS2 (Lipin/Ned1/Smp2)
      pfam16876
      Location:475565
      Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

    Alternate Rn_Celera

    Genomic

    1. AC_000077.1 Alternate Rn_Celera

      Range
      108213668..108287163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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