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    Ap3b1 adaptor-related protein complex 3, beta 1 subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309969, updated on 8-Apr-2018
    Official Symbol
    Ap3b1provided by RGD
    Official Full Name
    adaptor-related protein complex 3, beta 1 subunitprovided by RGD
    Primary source
    RGD:1310256
    See related
    Ensembl:ENSRNOG00000010624
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Adrenal (RPKM 169.3), Thymus (RPKM 132.0) and 9 other tissues See more
    Orthologs
    Location:
    2q12
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (24022815..24227522)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (43195152..43397102)

    Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene LHFPL tetraspan subfamily member 2 Neighboring gene similar to small nuclear ribonucleoparticle-associated protein Neighboring gene secretory carrier membrane protein 1 Neighboring gene uncharacterized LOC108349922 Neighboring gene tubulin folding cofactor A

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    GTP-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTP-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    anterograde axonal transport ISO
    Inferred from Sequence Orthology
    more info
     
    anterograde synaptic vesicle transport IEA
    Inferred from Electronic Annotation
    more info
     
    anterograde synaptic vesicle transport ISO
    Inferred from Sequence Orthology
    more info
     
    antigen processing and presentation ISO
    Inferred from Sequence Orthology
    more info
     
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
     
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib ISO
    Inferred from Sequence Orthology
    more info
     
    biological_process ND
    No biological Data available
    more info
     
    blood coagulation IEA
    Inferred from Electronic Annotation
    more info
     
    blood coagulation ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    melanosome organization IEA
    Inferred from Electronic Annotation
    more info
     
    melanosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NK T cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of NK T cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    protein targeting to lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    protein targeting to lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    AP-3 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    axon cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cellular_component ND
    No biological Data available
    more info
     
    clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    AP-3 complex subunit beta-1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107646.1NP_001101116.1  AP-3 complex subunit beta-1

      See identical proteins and their annotated locations for NP_001101116.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473955
      UniProtKB/TrEMBL
      D3ZIF5
      Related
      ENSRNOP00000060116.1, ENSRNOT00000066302.1
      Conserved Domains (3) summary
      pfam01602
      Location:1269
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:502646
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal
      pfam14797
      Location:413454
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

      Range
      24022815..24227522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006231814.3XP_006231876.1  AP-3 complex subunit beta-1 isoform X1

      See identical proteins and their annotated locations for XP_006231876.1

      UniProtKB/TrEMBL
      A0A0G2JWD6
      Related
      ENSRNOP00000069838.1, ENSRNOT00000089599.1
      Conserved Domains (5) summary
      pfam01602
      Location:46583
      Adaptin_N; Adaptin N terminal region
      pfam12717
      Location:128251
      Cnd1; non-SMC mitotic condensation complex subunit 1
      pfam14796
      Location:816960
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal
      pfam14797
      Location:727768
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      sd00044
      Location:116144
      HEAT; HEAT repeat [structural motif]

    RNA

    1. XR_001836452.1 RNA Sequence

    Alternate Rn_Celera

    Genomic

    1. AC_000070.1 Alternate Rn_Celera

      Range
      21672156..21872572
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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