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    Mc3r melanocortin 3 receptor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29310, updated on 18-Sep-2018

    Summary

    Official Symbol
    Mc3rprovided by RGD
    Official Full Name
    melanocortin 3 receptorprovided by RGD
    Primary source
    RGD:3056
    See related
    Ensembl:ENSRNOG00000004451
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    receptor for corticotropin (ACTH) and melanotropin (MSH) [RGD, Feb 2006]
    Orthologs

    Genomic context

    See Mc3r in Genome Data Viewer
    Location:
    3q42
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (170252901..170253998)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (176331172..176332269)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691983 Neighboring gene cerebellin 4 precursor Neighboring gene uncharacterized LOC102549927 Neighboring gene similar to maternal G10 transcript

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    melanocortin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    melanocortin receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    melanocyte-stimulating hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    melanocyte-stimulating hormone receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    neuropeptide binding IEA
    Inferred from Electronic Annotation
    more info
     
    neuropeptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    peptide hormone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptide hormone binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    adenylate cyclase-activating G protein-coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    circadian regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    circadian regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    homoiothermy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    locomotor rhythm ISO
    Inferred from Sequence Orthology
    more info
     
    locomotor rhythm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of blood pressure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of feeding behavior ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of feeding behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of heart rate IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sodium ion homeostasis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    melanocortin receptor 3
    Names
    MC3-R

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025270.3NP_001020441.3  melanocortin receptor 3

      See identical proteins and their annotated locations for NP_001020441.3

      Status: PROVISIONAL

      Source sequence(s)
      AY671938
      UniProtKB/Swiss-Prot
      P32244
      Related
      ENSRNOP00000005871.3, ENSRNOT00000005871.4
      Conserved Domains (2) summary
      pfam00001
      Location:55299
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:45170
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      170252901..170253998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      160219693..160220790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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