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    Hdx highly divergent homeobox [ Mus musculus (house mouse) ]

    Gene ID: 245596, updated on 7-Aug-2018

    Summary

    Official Symbol
    Hdxprovided by MGI
    Official Full Name
    highly divergent homeoboxprovided by MGI
    Primary source
    MGI:MGI:2685226
    See related
    Ensembl:ENSMUSG00000034551 Vega:OTTMUSG00000018434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm380; D030011N01Rik
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See Hdx in Genome Data Viewer
    Location:
    X; X E1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (111575204..111697079, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (108688813..108810688, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S6 kinase polypeptide 6 Neighboring gene predicted gene 7340 Neighboring gene guanosine diphosphate (GDP) dissociation inhibitor 2 pseudogene Neighboring gene testis expressed gene 16 Neighboring gene transmembrane 9 superfamily member 3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080549.2NP_001074018.1  highly divergent homeobox isoform 1

      See identical proteins and their annotated locations for NP_001074018.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK083436, BC116300, CJ060144
      Consensus CDS
      CCDS41105.1
      UniProtKB/Swiss-Prot
      Q14B70
      Related
      ENSMUSP00000109049.2, OTTMUSP00000019993, ENSMUST00000113422.8, OTTMUST00000044483
      Conserved Domains (2) summary
      smart00389
      Location:459
      HOX; Homeodomain
      cd00086
      Location:441497
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    2. NM_001290459.1NP_001277388.1  highly divergent homeobox isoform 2

      See identical proteins and their annotated locations for NP_001277388.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a portion of the 5' coding region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1.
      Source sequence(s)
      AK083436, BC116300, CJ060144
      Consensus CDS
      CCDS72422.1
      UniProtKB/Swiss-Prot
      Q14B70
      Related
      ENSMUSP00000043482.5, OTTMUSP00000019994, ENSMUST00000038472.6, OTTMUST00000044484
      Conserved Domains (1) summary
      cd00086
      Location:383439
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      111575204..111697079 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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