Format

Send to:

Choose Destination
    • Showing Current items.

    R3HCC1 R3H domain and coiled-coil containing 1 [ Homo sapiens (human) ]

    Gene ID: 203069, updated on 11-Jun-2021

    Summary

    Official Symbol
    R3HCC1provided by HGNC
    Official Full Name
    R3H domain and coiled-coil containing 1provided by HGNC
    Primary source
    HGNC:HGNC:27329
    See related
    Ensembl:ENSG00000104679
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in testis (RPKM 16.1), fat (RPKM 12.3) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See R3HCC1 in Genome Data Viewer
    Location:
    8p21.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (23288092..23296279)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (23145605..23153792)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379326 Neighboring gene charged multivesicular body protein 7 Neighboring gene lysyl oxidase like 2 Neighboring gene uncharacterized LOC100507156 Neighboring gene ectonucleoside triphosphate diphosphohydrolase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • DKFZp564N123

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    R3H and coiled-coil domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136108.3NP_001129580.2  R3H and coiled-coil domain-containing protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
      Source sequence(s)
      BC032421, BC143829
      Consensus CDS
      CCDS47826.2
      UniProtKB/Swiss-Prot
      Q9Y3T6
      Related
      ENSP00000265806.8, ENST00000265806.12
      Conserved Domains (2) summary
      cd02638
      Location:1980
      R3H_unknown_1; R3H domain of a group of eukaryotic proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in ...
      cl17169
      Location:318382
      RRM_SF; RNA recognition motif (RRM) superfamily
    2. NM_001301650.2NP_001288579.1  R3H and coiled-coil domain-containing protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame segment in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
      Source sequence(s)
      BC032421, BC143822
      Consensus CDS
      CCDS78317.1
      UniProtKB/Swiss-Prot
      Q9Y3T6
      Related
      ENSP00000486278.2, ENST00000625275.3
      Conserved Domains (2) summary
      cd02638
      Location:1980
      R3H_unknown_1; R3H domain of a group of eukaryotic proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in ...
      cl17169
      Location:276340
      RRM_SF; RNA recognition motif (RRM) superfamily

    RNA

    1. NR_125897.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC032421, BC143827

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      23288092..23296279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center