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    Nkx2-3 NK2 homeobox 3 [ Mus musculus (house mouse) ]

    Gene ID: 18089, updated on 8-Jul-2018
    Official Symbol
    Nkx2-3provided by MGI
    Official Full Name
    NK2 homeobox 3provided by MGI
    Primary source
    MGI:MGI:97348
    See related
    Ensembl:ENSMUSG00000044220 Vega:OTTMUSG00000029846
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nkx2.3; tinman; Nkx-2.3
    Expression
    Biased expression in duodenum adult (RPKM 12.0), colon adult (RPKM 9.9) and 6 other tissues See more
    Orthologs
    See Nkx2-3 in Genome Data Viewer
    Location:
    19 C3; 19 36.67 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (43612325..43615892)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (43686815..43690382)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted gene 20467 Neighboring gene predicted gene, 46656 Neighboring gene predicted gene 4311 Neighboring gene predicted gene, 34922

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    CD4-positive, alpha-beta T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Peyer's patch development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    digestive tract development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gland morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lymph node development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    macrophage differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mucosal-associated lymphoid tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    odontogenesis of dentin-containing tooth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasma cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    post-embryonic digestive tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    spleen development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    triglyceride metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    homeobox protein Nkx-2.3
    Names
    Drosophila NK2 transcription factor related, locus 3
    NK2 transcription factor related, locus 3
    homeobox protein NK-2 homolog 3
    homeobox protein NK-2 homolog C
    nkx2-C

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008699.2NP_032725.1  homeobox protein Nkx-2.3

      See identical proteins and their annotated locations for NP_032725.1

      Status: PROVISIONAL

      Source sequence(s)
      BC072614
      Consensus CDS
      CCDS29833.1
      UniProtKB/Swiss-Prot
      P97334
      Related
      ENSMUSP00000050933.9, OTTMUSP00000038428, ENSMUST00000057178.10, OTTMUST00000074066
      Conserved Domains (1) summary
      smart00389
      Location:145201
      HOX; Homeodomain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      43612325..43615892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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