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    pam-1 Puromycin-sensitive aminopeptidase [ Caenorhabditis elegans ]

    Gene ID: 177528, updated on 19-Aug-2018

    Summary

    Gene symbol
    pam-1
    Gene description
    Puromycin-sensitive aminopeptidase
    Primary source
    WormBase:WBGene00003914
    Locus tag
    CELE_F49E8.3
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See pam-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (7544140..7550804, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene Cytidine deaminase Neighboring gene Oocyte Excluded Factor Neighboring gene Protein dif-1 Neighboring gene hypothetical protein

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    metalloaminopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metalloaminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    anterior/posterior axis specification, embryo IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    embryo development ending in birth or egg hatching IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    exit from meiosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    first cell cycle pseudocleavage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    maintenance of centrosome location IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    maintenance of centrosome location IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    oogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    peptide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptide catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of oocyte maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of meiotic cell cycle process involved in oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of meiotic cell cycle process involved in oocyte maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of oviposition IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of oviposition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell cortex IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    condensed chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic spindle pole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spindle pole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Puromycin-sensitive aminopeptidase
    NP_001023209.1
    • Confirmed by transcript evidence
    NP_001023210.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7544140..7550804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028039.1NP_001023210.1  Puromycin-sensitive aminopeptidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023210.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4TT88
      Conserved Domains (2) summary
      cd09601
      Location:87529
      M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
      pfam11838
      Location:602927
      ERAP1_C; ERAP1-like C-terminal domain
    2. NM_001028038.4NP_001023209.1  Puromycin-sensitive aminopeptidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023209.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4TT88
      Conserved Domains (3) summary
      cd09601
      Location:23465
      M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
      pfam01433
      Location:15402
      Peptidase_M1; Peptidase family M1
      pfam11838
      Location:539860
      ERAP1_C; ERAP1-like C-terminal domain
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