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    cdk-5 Cyclin-dependent-like kinase 5 [ Caenorhabditis elegans ]

    Gene ID: 176774, updated on 12-Aug-2018

    Summary

    Gene symbol
    cdk-5
    Gene description
    Cyclin-dependent-like kinase 5
    Primary source
    WormBase:WBGene00000407
    Locus tag
    CELE_T27E9.3
    Gene type
    protein coding
    RNA name
    Cyclin-dependent-like kinase 5
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See cdk-5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (13464818..13466295, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cytochrome b-c1 complex subunit 6 Neighboring gene Adenine Nucleotide Translocator Neighboring gene KELch-repeat containing protein Neighboring gene PhosphatidylSerine SYnthase

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    chemical synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment or maintenance of microtubule cytoskeleton polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of dense core granule transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    neuron apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of dense core granule transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of protein transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of synapse assembly IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of neuron remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT regulation of synaptic vesicle transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of terminal button organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    synaptic transmission, GABAergic IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    synaptic transmission, GABAergic IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    synaptic vesicle transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synaptic vesicle transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendrite IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Cyclin-dependent-like kinase 5
    NP_499783.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13464818..13466295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067382.7NP_499783.1  Cyclin-dependent-like kinase 5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499783.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5ECH7
      Conserved Domains (2) summary
      cd07839
      Location:3286
      STKc_CDK5; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 5
      PLN00009
      Location:1292
      PLN00009; cyclin-dependent kinase A; Provisional
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