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    Gnb3 guanine nucleotide binding protein (G protein), beta 3 [ Mus musculus (house mouse) ]

    Gene ID: 14695, updated on 3-Jun-2018
    Official Symbol
    Gnb3provided by MGI
    Official Full Name
    guanine nucleotide binding protein (G protein), beta 3provided by MGI
    Primary source
    MGI:MGI:95785
    See related
    Ensembl:ENSMUSG00000023439 Vega:OTTMUSG00000027058
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gnb-3
    Expression
    Biased expression in adrenal adult (RPKM 3.8), heart adult (RPKM 3.5) and 9 other tissues See more
    Orthologs
    See Gnb3 in Genome Data Viewer
    Location:
    6 F2; 6 59.17 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (124834240..124840275, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (124784258..124790293, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 5 (isopeptidase T) Neighboring gene cell division cycle associated 3 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene predicted gene, 32404

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    spectrin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    cell volume homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cholesterol metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of glucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of hormone metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of phospholipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of triglyceride metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell body ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterotrimeric G-protein complex TAS
    Traceable Author Statement
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
    Names
    transducin beta chain 3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013530.1NP_038558.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

      See identical proteins and their annotated locations for NP_038558.1

      Status: VALIDATED

      Source sequence(s)
      BC018239
      Consensus CDS
      CCDS20532.1
      UniProtKB/Swiss-Prot
      Q61011
      UniProtKB/TrEMBL
      Q54AE3
      Related
      ENSMUSP00000024206.5, OTTMUSP00000033588, ENSMUST00000024206.5, OTTMUST00000066896
      Conserved Domains (3) summary
      COG2319
      Location:49340
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:48340
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:5895
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      124834240..124840275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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