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    KCTD19 potassium channel tetramerization domain containing 19 [ Homo sapiens (human) ]

    Gene ID: 146212, updated on 17-Jun-2019

    Summary

    Official Symbol
    KCTD19provided by HGNC
    Official Full Name
    potassium channel tetramerization domain containing 19provided by HGNC
    Primary source
    HGNC:HGNC:24753
    See related
    Ensembl:ENSG00000168676
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 29.8) See more
    Orthologs

    Genomic context

    See KCTD19 in Genome Data Viewer
    Location:
    16q22.1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (67289432..67326741, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (67323338..67360664, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene formin homology 2 domain containing 1 Neighboring gene solute carrier family 9 member A5 Neighboring gene pleckstrin homology and RhoGEF domain containing G4 Neighboring gene RN7SK pseudogene 118 Neighboring gene leucine rich repeat containing 36 Neighboring gene RNA, U1 small nuclear 123, pseudogene Neighboring gene tubulin polymerization promoting protein family member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Nef nef HIV-1 Nef-mediated downregulation of HLA (MHCI) may be affected by/inhibited by KCTD19 as demonstrated by siRNA genome-wide screen [in HeLa cells) PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ40162

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein KCTD19
    Names
    potassium channel tetramerisation domain containing 19
    testicular tissue protein Li 101

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_053040.1 RefSeqGene

      Range
      4988..42327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001100915.3NP_001094385.1  BTB/POZ domain-containing protein KCTD19

      See identical proteins and their annotated locations for NP_001094385.1

      Status: VALIDATED

      Source sequence(s)
      BC094790, BC117335
      Consensus CDS
      CCDS42179.1
      UniProtKB/Swiss-Prot
      Q17RG1
      Related
      ENSP00000305702.5, ENST00000304372.6
      Conserved Domains (1) summary
      cl02518
      Location:1872
      BTB; BTB/POZ domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

      Range
      67289432..67326741 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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