Format

Send to:

Choose Destination
    • Showing Current items.

    Gbx2 gastrulation brain homeobox 2 [ Mus musculus (house mouse) ]

    Gene ID: 14472, updated on 19-Jun-2018
    Official Symbol
    Gbx2provided by MGI
    Official Full Name
    gastrulation brain homeobox 2provided by MGI
    Primary source
    MGI:MGI:95668
    See related
    Ensembl:ENSMUSG00000034486 Vega:OTTMUSG00000037278
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gbx-2; MMoxA; Stra7; D130058E05Rik
    Expression
    Biased expression in whole brain E14.5 (RPKM 10.0), CNS E14 (RPKM 6.9) and 5 other tissues See more
    Orthologs
    See Gbx2 in Genome Data Viewer
    Location:
    1 D; 1 45.06 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (89927962..89931176, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (91824537..91827751, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 Neighboring gene predicted gene 28499 Neighboring gene predicted gene, 41914 Neighboring gene RIKEN cDNA 4933400F21 gene Neighboring gene uncharacterized LOC102637806 Neighboring gene predicted gene, 41915 Neighboring gene ankyrin repeat and SOCS box-containing 18 Neighboring gene predicted gene, 34616

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Dopaminergic Neurogenesis, organism-specific biosystem (from WikiPathways)
      Dopaminergic Neurogenesis, organism-specific biosystemhttps://www.michaeljfox.org/foundation/grant-detail.php?grant_id=141
    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    autonomic nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    branching involved in blood vessel morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    branching involved in blood vessel morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cerebellar granule cell precursor proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cerebellum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    forebrain neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hindbrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inner ear morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    midbrain-hindbrain boundary development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    midbrain-hindbrain boundary morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural crest cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    rhombomere 2 development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    thalamus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    tube morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    homeobox protein GBX-2
    Names
    gastrulation and brain-specific homeobox protein 2
    stimulated by retinoic acid gene 7 protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010262.3NP_034392.1  homeobox protein GBX-2

      See identical proteins and their annotated locations for NP_034392.1

      Status: VALIDATED

      Source sequence(s)
      AC124227
      Consensus CDS
      CCDS15150.1
      UniProtKB/Swiss-Prot
      P48031
      Related
      ENSMUSP00000048508.7, OTTMUSP00000053702, ENSMUST00000036954.8, OTTMUST00000096174
      Conserved Domains (1) summary
      pfam00046
      Location:250303
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      89927962..89931176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center