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    Etv1 ets variant 1 [ Mus musculus (house mouse) ]

    Gene ID: 14009, updated on 17-Oct-2018

    Summary

    Official Symbol
    Etv1provided by MGI
    Official Full Name
    ets variant 1provided by MGI
    Primary source
    MGI:MGI:99254
    See related
    Ensembl:ENSMUSG00000004151 Vega:OTTMUSG00000035098
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ER81; Etsrp81
    Expression
    Biased expression in cerebellum adult (RPKM 13.2), frontal lobe adult (RPKM 4.0) and 9 other tissues See more
    Orthologs

    Genomic context

    See Etv1 in Genome Data Viewer
    Location:
    12 A3; 12 17.99 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (38779656..38868215)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (39506845..39594802)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase, beta Neighboring gene RIKEN cDNA 4930428E07 gene Neighboring gene phosphatidylethanolamine binding protein 2 pseudogene Neighboring gene ribosomal protein, large, P0 pseudogene Neighboring gene predicted gene, 34611

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mechanosensory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    peripheral nervous system neuron development IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ETS translocation variant 1
    Names
    ets variant gene 1
    ets-related protein 81

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163154.1NP_001156626.1  ETS translocation variant 1 isoform b

      See identical proteins and their annotated locations for NP_001156626.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promoter, 5' UTR, and 5' coding region, compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AK032224, CD776508
      Consensus CDS
      CCDS49054.1
      UniProtKB/TrEMBL
      Q8CCR6
      Related
      ENSMUSP00000125676.1, OTTMUSP00000048764, ENSMUST00000159334.7, OTTMUST00000089278
      Conserved Domains (2) summary
      smart00413
      Location:294378
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:21293
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    2. NM_001347379.1NP_001334308.1  ETS translocation variant 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (c) has the same N- and C-termini, but is shorter than isoform a.
      Source sequence(s)
      AK032224, AK035914, BB751428, CD776508, CT009742
      Consensus CDS
      CCDS83959.1
      UniProtKB/TrEMBL
      E0CZ54, Q8CCR6
    3. NM_007960.5NP_031986.1  ETS translocation variant 1 isoform a

      See identical proteins and their annotated locations for NP_031986.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AK032224, AK035914, BB751428, CD776508, CT009742
      Consensus CDS
      CCDS49053.1
      UniProtKB/Swiss-Prot
      P41164
      UniProtKB/TrEMBL
      Q549J8, Q8CCR6
      Related
      ENSMUSP00000093442.3, OTTMUSP00000048763, ENSMUST00000095767.10, OTTMUST00000089277
      Conserved Domains (2) summary
      smart00413
      Location:334418
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:2333
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      38779656..38868215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514967.2XP_006515030.1  ETS translocation variant 1 isoform X4

      Related
      ENSMUSP00000125692.1, OTTMUSP00000048767, ENSMUST00000160856.7, OTTMUST00000089281
      Conserved Domains (2) summary
      smart00413
      Location:316400
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:1315
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    2. XM_006514965.2XP_006515028.1  ETS translocation variant 1 isoform X2

      See identical proteins and their annotated locations for XP_006515028.1

      UniProtKB/Swiss-Prot
      P41164
      UniProtKB/TrEMBL
      Q549J8
      Related
      ENSMUSP00000125157.1, OTTMUSP00000048765, ENSMUST00000162563.7, OTTMUST00000089279
      Conserved Domains (2) summary
      smart00413
      Location:334418
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:2333
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    3. XM_006514964.3XP_006515027.1  ETS translocation variant 1 isoform X1

      Conserved Domains (2) summary
      smart00413
      Location:350434
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:31349
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    4. XM_006514966.3XP_006515029.1  ETS translocation variant 1 isoform X3

      Conserved Domains (2) summary
      smart00413
      Location:332416
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:31331
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    5. XM_006514972.3XP_006515035.1  ETS translocation variant 1 isoform X9

      Conserved Domains (2) summary
      smart00413
      Location:203287
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:3202
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    6. XM_006514968.3XP_006515031.1  ETS translocation variant 1 isoform X5

      See identical proteins and their annotated locations for XP_006515031.1

      UniProtKB/TrEMBL
      Q8CCR6
      Conserved Domains (2) summary
      smart00413
      Location:294378
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:21293
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    7. XM_006514971.3XP_006515034.1  ETS translocation variant 1 isoform X8

      UniProtKB/TrEMBL
      E0CXD2
      Related
      ENSMUSP00000124736.1, OTTMUSP00000048768, ENSMUST00000161980.7, OTTMUST00000089282
      Conserved Domains (2) summary
      smart00413
      Location:276360
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:21275
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    8. XM_006514970.3XP_006515033.1  ETS translocation variant 1 isoform X7

      Conserved Domains (2) summary
      smart00413
      Location:278362
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:2277
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
    9. XM_006514969.3XP_006515032.1  ETS translocation variant 1 isoform X6

      Conserved Domains (2) summary
      smart00413
      Location:279363
      ETS; erythroblast transformation specific domain
      pfam04621
      Location:24278
      ETS_PEA3_N; PEA3 subfamily ETS-domain transcription factor N terminal domain
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