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    Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon [ Mus musculus (house mouse) ]

    Gene ID: 110794, updated on 2-Oct-2018

    Summary

    Official Symbol
    Cebpeprovided by MGI
    Official Full Name
    CCAAT/enhancer binding protein (C/EBP), epsilonprovided by MGI
    Primary source
    MGI:MGI:103572
    See related
    Ensembl:ENSMUSG00000052435
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CRP1; Gm294; C/EBPe; C/EBPepsilon
    Expression
    Biased expression in liver E18 (RPKM 15.2), liver adult (RPKM 4.7) and 9 other tissues See more
    Orthologs

    Genomic context

    See Cebpe in Genome Data Viewer
    Location:
    14 C2; 14 27.9 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (54710363..54712174, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55329200..55331011, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene apoptotic chromatin condensation inducer 1 Neighboring gene RIKEN cDNA 1700123O20 gene Neighboring gene predicted gene, 29776 Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 Neighboring gene ring finger protein 212B Neighboring gene developmental pluripotency-associated protein 5A-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC124002, MGC124003

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cytokine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    granulocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    macrophage differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phagocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    CCAAT/enhancer-binding protein epsilon
    Names
    C/EBP-related protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207131.1NP_997014.1  CCAAT/enhancer-binding protein epsilon

      See identical proteins and their annotated locations for NP_997014.1

      Status: VALIDATED

      Source sequence(s)
      AY570294
      Consensus CDS
      CCDS27100.1
      UniProtKB/Swiss-Prot
      Q6PZD9
      Related
      ENSMUSP00000068927.6, ENSMUST00000064290.7
      Conserved Domains (1) summary
      cd14715
      Location:202262
      bZIP_CEBPE; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein epsilon (CEBPE): a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      54710363..54712174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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