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    dhx57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [ Cynoglossus semilaevis (tongue sole) ]

    Gene ID: 103382889, updated on 5-Aug-2026
    Gene symbol
    dhx57
    Gene description
    DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
    See related
    Ensembl:ENSCSEG00000011346
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cynoglossus semilaevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See dhx57 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2025_06 current Cse_v1.0 (GCF_000523025.1) 8 NC_024314.1 (25486228..25496552, complement)

    Chromosome 8 - NC_024314.1Genomic Context describing neighboring genes Neighboring gene troponin T2e, cardiac Neighboring gene dynamin-1-like protein Neighboring gene short transmembrane mitochondrial protein 1 Neighboring gene small lysine rich protein 1 Neighboring gene MORN repeat containing 2 Neighboring gene striatin interacting protein 2 Neighboring gene adenosylhomocysteinase like 2b

    Genomic Sequence:
    NC_024314.1 Chromosome 8 Reference Cse_v1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    putative ATP-dependent RNA helicase DHX57
    Names
    DEAH-box helicase 57
    DExH-box helicase 57

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000523025.1-RS_2025_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cse_v1.0 Primary Assembly

    Genomic

    1. NC_024314.1 Reference Cse_v1.0 Primary Assembly

      Range
      25486228..25496552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017034691.2 → XP_016890180.1  putative ATP-dependent RNA helicase DHX57

      UniProtKB/TrEMBL
      A0A3P8VTR5, A0A3P8VTV4
      Related
      ENSCSEP00000017744.1, ENSCSET00000017964.1
      Conserved Domains (8) summary
      smart00487
      Location:596 → 786
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:1102 → 1184
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:617 → 759
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd14317
      Location:218 → 255
      UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
      pfam00271
      Location:891 → 1027
      Helicase_C; Helicase conserved C-terminal domain
      pfam00642
      Location:340 → 362
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam05773
      Location:280 → 459
      RWD; RWD domain
      pfam07717
      Location:1223 → 1370
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    2. XM_017034692.2 → XP_016890181.1  putative ATP-dependent RNA helicase DHX57

      UniProtKB/TrEMBL
      A0A3P8VTR5, A0A3P8VTV4
      Conserved Domains (8) summary
      smart00487
      Location:596 → 786
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:1102 → 1184
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:617 → 759
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd14317
      Location:218 → 255
      UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
      pfam00271
      Location:891 → 1027
      Helicase_C; Helicase conserved C-terminal domain
      pfam00642
      Location:340 → 362
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam05773
      Location:280 → 459
      RWD; RWD domain
      pfam07717
      Location:1223 → 1370
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    3. XM_008315859.3 → XP_008314081.1  putative ATP-dependent RNA helicase DHX57

      UniProtKB/TrEMBL
      A0A3P8VTR5, A0A3P8VTV4
      Conserved Domains (8) summary
      smart00487
      Location:596 → 786
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:1102 → 1184
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:617 → 759
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd14317
      Location:218 → 255
      UBA_DHX57; UBA domain found in putative ATP-dependent RNA helicase DHX57 and similar proteins
      pfam00271
      Location:891 → 1027
      Helicase_C; Helicase conserved C-terminal domain
      pfam00642
      Location:340 → 362
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam05773
      Location:280 → 459
      RWD; RWD domain
      pfam07717
      Location:1223 → 1370
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Nucleotide Protein
    Heading Accession and Version

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