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    prpf8 pre-mRNA processing factor 8 [ Xiphophorus maculatus (southern platyfish) ]

    Gene ID: 102224828, updated on 10-Mar-2024
    Gene symbol
    prpf8
    Gene description
    pre-mRNA processing factor 8
    See related
    Ensembl:ENSXMAG00000008505
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xiphophorus maculatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See prpf8 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    102 current X_maculatus-5.0-male (GCF_002775205.1) 18 NC_036460.1 (20320082..20336430, complement)
    101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372236.1 (906941..923373, complement)

    Chromosome 18 - NC_036460.1Genomic Context describing neighboring genes Neighboring gene vitronectin a Neighboring gene scavenger receptor class F, member 1 Neighboring gene Rab interacting lysosomal protein Neighboring gene uncharacterized LOC102231770 Neighboring gene piggyBac transposable element-derived protein 4-like

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables U1 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U2 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U5 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U6 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pre-mRNA intronic binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spliceosomal tri-snRNP complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U5 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Preferred Names
    pre-mRNA-processing-splicing factor 8

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference X_maculatus-5.0-male Primary Assembly

    Genomic

    1. NC_036460.1 Reference X_maculatus-5.0-male Primary Assembly

      Range
      20320082..20336430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014469526.2 → XP_014325012.1  pre-mRNA-processing-splicing factor 8

      UniProtKB/TrEMBL
      M4A265
      Related
      ENSXMAP00000008559.2, ENSXMAT00000008572.2
      Conserved Domains (8) summary
      cd08056
      Location:2090 → 2340
      MPN_PRP8; Mpr1p, Pad1p N-terminal (MPN) domains without isopeptidase activity found in splicing factor Prp8
      COG5178
      Location:50 → 2357
      PRP8; U5 snRNP spliceosome subunit [RNA processing and modification]
      cd13838
      Location:1789 → 2039
      RNase_H_like_Prp8_IV; Ribonuclease-like Prp8 domain IV core
      pfam08082
      Location:81 → 231
      PRO8NT; PRO8NT (NUC069), PrP8 N-terminal domain
      pfam08083
      Location:419 → 819
      PROCN; PROCN (NUC071) domain
      pfam10596
      Location:1465 → 1623
      U6-snRNA_bdg; U6-snRNA interacting domain of PrP8
      pfam10597
      Location:1233 → 1365
      U5_2-snRNA_bdg; U5-snRNA binding site 2 of PrP8
      pfam10598
      Location:1009 → 1100
      RRM_4; RNA recognition motif of the spliceosomal PrP8
    Nucleotide Protein Strain
    Heading Accession and Version

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    Molecular Biology Databases