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    DHX58 DExH-box helicase 58 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100347525, updated on 17-Dec-2024

    Summary

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    Gene symbol
    DHX58
    Gene description
    DExH-box helicase 58
    See related
    Ensembl:ENSOCUG00000013278
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See DHX58 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 17 NC_091448.1 (20680019..20688436)
    RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 19 NC_067392.1 (40467410..40475803, complement)

    Chromosome 17 - NC_091448.1Genomic Context describing neighboring genes Neighboring gene heat shock protein family B (small) member 9 Neighboring gene lysine acetyltransferase 2A Neighboring gene zinc finger protein 385C Neighboring gene uncharacterized LOC138846077 Neighboring gene chromosome 17 C17orf113 homolog Neighboring gene NFKB inhibitor interacting Ras like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of viral sensing RIG-I-like receptor genes in Leporidae genera Oryctolagus, Sylvilagus, and Lepus. Lemos de Matos A, et al. Immunogenetics, 2014 Jan. PMID 24220721
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antiviral innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoplasmic pattern recognition receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of RIG-I signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DHX58
    Names
    DEXH (Asp-Glu-X-His) box polypeptide 58
    putative ATP-dependent RNA helicase DHX58

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOryCun1.1

    Genomic

    1. NC_091448.1 Reference mOryCun1.1

      Range
      20680019..20688436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_070060692.1 → XP_069916793.1  ATP-dependent RNA helicase DHX58 isoform X2

      UniProtKB/TrEMBL
      V5TDD0, V5TF12

    2. XM_002719391.5 → XP_002719437.3  ATP-dependent RNA helicase DHX58 isoform X1

      UniProtKB/TrEMBL
      V5TF12
    Nucleotide Protein
    Heading Accession and Version

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