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    lrrk2 leucine-rich repeat kinase 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100145062, updated on 20-Jun-2018
    Symbol
    lrrk2provided by Xenbase
    Full Name
    leucine-rich repeat kinase 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5768572
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    See lrrk2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    55
    Annotation release Status Assembly Chr Location
    103 current Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (65846308..65947243)
    102 previous assembly Xtropicalis_v7 (GCF_000004195.2) Unplaced Scaffold NW_004668234.1 (103901696..104002638)

    Chromosome 3 - NC_030679.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 13 Neighboring gene uncharacterized LOC105946846 Neighboring gene uncharacterized LOC108646165 Neighboring gene uncharacterized LOC105946847 Neighboring gene sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)

    Homology

    Preferred Names
    leucine-rich repeat serine/threonine-protein kinase 2

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_tropicalis_v9.1 Primary Assembly

    Genomic

    1. NC_030679.1 Reference Xenopus_tropicalis_v9.1 Primary Assembly

      Range
      65846308..65947243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012959985.2XP_012815439.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X1

      See identical proteins and their annotated locations for XP_012815439.1

      Conserved Domains (7) summary
      smart00220
      Location:18762125
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG4886
      Location:9571273
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14068
      Location:18762127
      STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
      sd00033
      Location:10051028
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00071
      Location:13281502
      Ras; Ras family
      pfam16095
      Location:15161732
      COR; C-terminal of Roc, COR, domain
      cl21455
      Location:13261499
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. XM_002932204.4XP_002932250.2  leucine-rich repeat serine/threonine-protein kinase 2 isoform X1

      See identical proteins and their annotated locations for XP_002932250.2

      Conserved Domains (7) summary
      smart00220
      Location:18762125
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG4886
      Location:9571273
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14068
      Location:18762127
      STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
      sd00033
      Location:10051028
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00071
      Location:13281502
      Ras; Ras family
      pfam16095
      Location:15161732
      COR; C-terminal of Roc, COR, domain
      cl21455
      Location:13261499
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    3. XM_012959987.2XP_012815441.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X2

      Conserved Domains (7) summary
      smart00220
      Location:18362085
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG4886
      Location:9171233
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14068
      Location:18362087
      STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
      sd00033
      Location:965988
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00071
      Location:12881462
      Ras; Ras family
      pfam16095
      Location:14761692
      COR; C-terminal of Roc, COR, domain
      cl21455
      Location:12861459
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    4. XM_012959988.2XP_012815442.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X3

      Conserved Domains (7) summary
      smart00220
      Location:18312080
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG4886
      Location:9121228
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14068
      Location:18312082
      STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
      sd00033
      Location:960983
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00071
      Location:12831457
      Ras; Ras family
      pfam16095
      Location:14711687
      COR; C-terminal of Roc, COR, domain
      cl21455
      Location:12811454
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    5. XM_012959986.2XP_012815440.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X1

      See identical proteins and their annotated locations for XP_012815440.1

      Conserved Domains (7) summary
      smart00220
      Location:18762125
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG4886
      Location:9571273
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd14068
      Location:18762127
      STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
      sd00033
      Location:10051028
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00071
      Location:13281502
      Ras; Ras family
      pfam16095
      Location:15161732
      COR; C-terminal of Roc, COR, domain
      cl21455
      Location:13261499
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    6. XM_018092315.1XP_017947804.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X4

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