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    ulk1 unc-51 like autophagy activating kinase 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100127200, updated on 20-Jun-2018

    Summary

    Official Symbol
    ulk1provided by Xenbase
    Official Full Name
    unc-51 like autophagy activating kinase 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-492029
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    atg1; unc51; unc51.1
    Orthologs

    Genomic context

    See ulk1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (148110497..148167893, complement)
    102 previous assembly Xtropicalis_v7 (GCF_000004195.2) Unplaced Scaffold NW_004668232.1 (51256103..51313392)

    Chromosome 1 - NC_030677.1Genomic Context describing neighboring genes Neighboring gene E1A-binding protein p400 Neighboring gene pseudouridylate synthase 1 Neighboring gene matrix metallopeptidase 17 Neighboring gene collagen alpha-1(I) chain-like

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Autophagy - animal, organism-specific biosystem (from KEGG)
      Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - animal, conserved biosystem (from KEGG)
      Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Cellular responses to stress, organism-specific biosystem (from REACTOME)
      Cellular responses to stress, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Macroautophagy, organism-specific biosystem (from REACTOME)
      Macroautophagy, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Membrane Trafficking, organism-specific biosystem (from REACTOME)
      Membrane Trafficking, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Mitophagy - animal, organism-specific biosystem (from KEGG)
      Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • Mitophagy - animal, conserved biosystem (from KEGG)
      Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • RAB GEFs exchange GTP for GDP on RABs, organism-specific biosystem (from REACTOME)
      RAB GEFs exchange GTP for GDP on RABs, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • TBC/RABGAPs, organism-specific biosystem (from REACTOME)
      TBC/RABGAPs, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Vesicle-mediated transport, organism-specific biosystem (from REACTOME)
      Vesicle-mediated transport, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • mTOR signaling pathway, organism-specific biosystem (from KEGG)
      mTOR signaling pathway, organism-specific biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...
    • mTOR signaling pathway, conserved biosystem (from KEGG)
      mTOR signaling pathway, conserved biosystemThe mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 conta...

    General gene information

    Homology

    General protein information

    Preferred Names
    serine/threonine-protein kinase ULK1
    Names
    unc-51-like kinase 1
    NP_001106388.1
    XP_012824388.1
    XP_012824415.1
    XP_012824444.1
    XP_017950932.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001112917.1NP_001106388.1  serine/threonine-protein kinase ULK1

      See identical proteins and their annotated locations for NP_001106388.1

      Status: PROVISIONAL

      Source sequence(s)
      BC154695
      UniProtKB/TrEMBL
      A8WGG0
      Conserved Domains (3) summary
      smart00220
      Location:9271
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14202
      Location:6272
      STKc_ULK1; Catalytic domain of the Serine/Threonine kinase, Unc-51-like kinase 1
      pfam12063
      Location:8351045
      DUF3543; Domain of unknown function (DUF3543)

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_tropicalis_v9.1 Primary Assembly

    Genomic

    1. NC_030677.1 Reference Xenopus_tropicalis_v9.1 Primary Assembly

      Range
      148110497..148167893 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012968990.2XP_012824444.1  serine/threonine-protein kinase ULK1 isoform X3

      Conserved Domains (3) summary
      smart00220
      Location:9271
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14202
      Location:6272
      STKc_ULK1; Catalytic domain of the Serine/Threonine kinase, Unc-51-like kinase 1
      pfam12063
      Location:8361046
      DUF3543; Domain of unknown function (DUF3543)
    2. XM_012968934.2XP_012824388.1  serine/threonine-protein kinase ULK1 isoform X1

      Conserved Domains (3) summary
      smart00220
      Location:9271
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14202
      Location:6272
      STKc_ULK1; Catalytic domain of the Serine/Threonine kinase, Unc-51-like kinase 1
      pfam12063
      Location:8371047
      DUF3543; Domain of unknown function (DUF3543)
    3. XM_012968961.2XP_012824415.1  serine/threonine-protein kinase ULK1 isoform X2

      Conserved Domains (3) summary
      smart00220
      Location:9271
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14202
      Location:6272
      STKc_ULK1; Catalytic domain of the Serine/Threonine kinase, Unc-51-like kinase 1
      pfam12063
      Location:8361046
      DUF3543; Domain of unknown function (DUF3543)
    4. XM_018095443.1XP_017950932.1  serine/threonine-protein kinase ULK1 isoform X4

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