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    HTR12 Histone superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839104, updated on 11-Oct-2018

    Summary

    Gene symbol
    HTR12
    Gene description
    Histone superfamily protein
    Primary source
    Araport:AT1G01370
    Locus tag
    AT1G01370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CENH3; CENTROMERIC HISTONE H3; F6F3.17; F6F3_17
    Summary
    Encodes a centromere-identifying protein histone H3 variant. Localized at centromeres in both mitotic and meiotic cells.

    Genomic context

    See HTR12 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (143489..146479)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Putative endonuclease or glycosyl hydrolase Neighboring gene regulatory component of ABA receptor 1 Neighboring gene Homeodomain-like superfamily protein Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene hypothetical protein

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001035850.3
    NM_001331270.1
    NM_100019.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleosomal DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    centromere complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    double fertilization forming a zygote and endosperm IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic chromosome separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nucleosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    condensed chromosome kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Histone superfamily protein
    NP_001030927.1
    • HTR12; FUNCTIONS IN: DNA binding; INVOLVED IN: double fertilization forming a zygote and endosperm; LOCATED IN: chromosome, centromeric region, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3 (InterPro:IPR000164), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: male-gamete-specific histone H3 (TAIR:AT1G19890.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_563627.1
    • HTR12; FUNCTIONS IN: DNA binding; INVOLVED IN: double fertilization forming a zygote and endosperm; LOCATED IN: chromosome, centromeric region, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3 (InterPro:IPR000164), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: male-gamete-specific histone H3 (TAIR:AT1G19890.1); Has 14361 Blast hits to 14354 proteins in 7190 species: Archae - 0; Bacteria - 0; Metazoa - 10494; Fungi - 2020; Plants - 1256; Viruses - 0; Other Eukaryotes - 591 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      143489..146479
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331269.1NP_001322867.1  Histone superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RVQ9
      UniProtKB/TrEMBL
      A0A178WB57
    2. NM_001035850.3NP_001030927.1  Histone superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030927.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RVQ9
      UniProtKB/TrEMBL
      A0A178WB57
      Conserved Domains (2) summary
      pfam00125
      Location:49171
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:72173
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
    3. NM_100019.2NP_563627.1  Histone superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563627.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RVQ9
      UniProtKB/TrEMBL
      A0A178WB57
      Conserved Domains (2) summary
      pfam00125
      Location:49171
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:72173
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
    4. NM_001331270.1NP_001322868.1  Histone superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RVQ9
      UniProtKB/TrEMBL
      A0A178WB57
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