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    Rab11a RAB11a, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

    Gene ID: 81830, updated on 2-Oct-2018

    Summary

    Official Symbol
    Rab11aprovided by RGD
    Official Full Name
    RAB11a, member RAS oncogene familyprovided by RGD
    Primary source
    RGD:619762
    See related
    Ensembl:ENSRNOG00000011302
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    GTP-binding protein [RGD, Feb 2006]
    Expression
    Biased expression in Brain (RPKM 466.1), Kidney (RPKM 461.4) and 9 other tissues See more
    Orthologs

    Genomic context

    See Rab11a in Genome Data Viewer
    Location:
    8q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (70192975..70215719, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (69896587..69919171, complement)

    Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene DIS3-like exosome 3'-5' exoribonuclease Neighboring gene multiple EGF-like-domains 11 Neighboring gene uncharacterized LOC102548470 Neighboring gene transfer RNA glutamine (anticodon CUG) Neighboring gene similar to 60S ribosomal protein L7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    GTP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTP binding TAS
    Traceable Author Statement
    more info
    PubMed 
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    myosin V binding IEA
    Inferred from Electronic Annotation
    more info
     
    myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    Rab protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    astral microtubule organization IEA
    Inferred from Electronic Annotation
    more info
     
    astral microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to organelle IEA
    Inferred from Electronic Annotation
    more info
     
    establishment of protein localization to organelle ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of vesicle localization ISO
    Inferred from Sequence Orthology
    more info
     
    exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exosomal secretion IEA
    Inferred from Electronic Annotation
    more info
     
    exosomal secretion ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular cholesterol transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    melanosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    melanosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    melanosome transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitotic metaphase plate congression IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle assembly IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body assembly IEA
    Inferred from Electronic Annotation
    more info
     
    multivesicular body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    neurotransmitter receptor transport, endosome to postsynaptic membrane EXP
    Inferred from Experiment
    more info
    PubMed 
    neurotransmitter receptor transport, endosome to postsynaptic membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neurotransmitter receptor transport, endosome to postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neurotransmitter receptor transport, endosome to postsynaptic membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of G2/M transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of G2/M transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of axon extension IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of long-term neuronal synaptic plasticity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of multivesicular body size IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of multivesicular body size ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    vesicle-mediated transport in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Schaffer collateral - CA1 synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cleavage furrow ISO
    Inferred from Sequence Orthology
    more info
     
    cleavage furrow ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    kinetochore microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with kinetochore microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule organizing center ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body IEA
    Inferred from Electronic Annotation
    more info
     
    multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    phagocytic vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic recycling endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    recycling endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    recycling endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    spindle pole IEA
    Inferred from Electronic Annotation
    more info
     
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     
    trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-11A
    Names
    24KG
    rab-11

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031152.2NP_112414.1  ras-related protein Rab-11A

      See identical proteins and their annotated locations for NP_112414.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085727
      UniProtKB/Swiss-Prot
      P62494
      Related
      ENSRNOP00000015598.3, ENSRNOT00000015598.3
      Conserved Domains (1) summary
      cd01868
      Location:9173
      Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

      Range
      70192975..70215719 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000076.1 Alternate Rn_Celera

      Range
      64627832..64650008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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