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    MAP9 microtubule associated protein 9 [ Homo sapiens (human) ]

    Gene ID: 79884, updated on 2-Oct-2018

    Summary

    Official Symbol
    MAP9provided by HGNC
    Official Full Name
    microtubule associated protein 9provided by HGNC
    Primary source
    HGNC:HGNC:26118
    See related
    Ensembl:ENSG00000164114 MIM:610070; Vega:OTTHUMG00000133628
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ASAP
    Summary
    ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]
    Expression
    Broad expression in brain (RPKM 7.7), thyroid (RPKM 7.3) and 23 other tissues See more
    Orthologs

    Genomic context

    See MAP9 in Genome Data Viewer
    Location:
    4q32.1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 4 NC_000004.12 (155342658..155376970, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (156263810..156298122, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y2 Neighboring gene uncharacterized LOC107986321 Neighboring gene uncharacterized LOC105377502 Neighboring gene uncharacterized LOC102724776 Neighboring gene TBC1 domain family member 3C pseudogene Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ21159

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    microtubule binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic spindle assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of mitotic centrosome separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    astral microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitotic spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitotic spindle midzone IEA
    Inferred from Electronic Annotation
    more info
     
    spindle midzone IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    microtubule-associated protein 9
    Names
    aster-associated protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039580.1NP_001034669.1  microtubule-associated protein 9

      See identical proteins and their annotated locations for NP_001034669.1

      Status: VALIDATED

      Source sequence(s)
      AC097467, AY690636, BC022852, CF144347
      Consensus CDS
      CCDS35493.1
      UniProtKB/Swiss-Prot
      Q49MG5
      UniProtKB/TrEMBL
      Q05CN5
      Related
      ENSP00000310593.4, OTTHUMP00000196622, ENST00000311277.8, OTTHUMT00000257771
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p12 Primary Assembly

      Range
      155342658..155376970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011532255.3XP_011530557.1  microtubule-associated protein 9 isoform X3

      Conserved Domains (1) summary
      cl01868
      Location:449525
      YukC; WXG100 protein secretion system (Wss), protein YukC
    2. XM_011532254.2XP_011530556.1  microtubule-associated protein 9 isoform X1

      See identical proteins and their annotated locations for XP_011530556.1

      UniProtKB/Swiss-Prot
      Q49MG5
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC
    3. XM_017008617.1XP_016864106.1  microtubule-associated protein 9 isoform X2

      Conserved Domains (1) summary
      cl01868
      Location:520596
      YukC; WXG100 protein secretion system (Wss), protein YukC
    4. XM_011532253.1XP_011530555.1  microtubule-associated protein 9 isoform X1

      See identical proteins and their annotated locations for XP_011530555.1

      UniProtKB/Swiss-Prot
      Q49MG5
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC
    5. XM_006714306.4XP_006714369.1  microtubule-associated protein 9 isoform X2

      Conserved Domains (1) summary
      cl01868
      Location:520596
      YukC; WXG100 protein secretion system (Wss), protein YukC
    6. XM_017008616.1XP_016864105.1  microtubule-associated protein 9 isoform X2

      Conserved Domains (1) summary
      cl01868
      Location:520596
      YukC; WXG100 protein secretion system (Wss), protein YukC
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