Format

Send to:

Choose Destination
    • Showing Current items.

    CPSF6 cleavage and polyadenylation specific factor 6 [ Bos taurus (cattle) ]

    Gene ID: 768231, updated on 21-Jan-2019

    Summary

    Official Symbol
    CPSF6provided by VGNC
    Official Full Name
    cleavage and polyadenylation specific factor 6provided by VGNC
    Primary source
    VGNC:VGNC:27674
    See related
    BGD:BT30461; Ensembl:ENSBTAG00000007323
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See CPSF6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 5 NC_037332.1 (44555923..44588479, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 5 AC_000162.1 (44761105..44793522, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene lysozyme Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene 40S ribosomal protein S20-like Neighboring gene small nucleolar RNA SNORA44

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
      mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
    • mRNA surveillance pathway, conserved biosystem (from KEGG)
      mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

    General gene information

    Homology

    Clone Names

    • MGC142454

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    exon-exon junction complex binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    ribosomal large subunit binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    mRNA alternative polyadenylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    messenger ribonucleoprotein complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of RNA export from nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein heterotetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    interchromatin granule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mRNA cleavage factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    paraspeckles ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    perichromatin fibrils ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    cleavage and polyadenylation specificity factor subunit 6
    Names
    cleavage and polyadenylation specific factor 6, 68 kD subunit
    cleavage and polyadenylation specific factor 6, 68kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078106.2NP_001071574.1  cleavage and polyadenylation specificity factor subunit 6

      See identical proteins and their annotated locations for NP_001071574.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120212
      UniProtKB/Swiss-Prot
      Q0P5D2
      Conserved Domains (1) summary
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      44555923..44588479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024992273.1XP_024848041.1  cleavage and polyadenylation specificity factor subunit 6 isoform X4

      Related
      ENSBTAP00000068135.1, ENSBTAT00000083441.1
      Conserved Domains (1) summary
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins
    2. XM_005206467.4XP_005206524.1  cleavage and polyadenylation specificity factor subunit 6 isoform X3

      See identical proteins and their annotated locations for XP_005206524.1

      Conserved Domains (1) summary
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins
    3. XM_005206466.4XP_005206523.1  cleavage and polyadenylation specificity factor subunit 6 isoform X2

      See identical proteins and their annotated locations for XP_005206523.1

      Related
      ENSBTAP00000047307.3, ENSBTAT00000050636.3
      Conserved Domains (2) summary
      COG0724
      Location:9152
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins
    4. XM_005206464.4XP_005206521.1  cleavage and polyadenylation specificity factor subunit 6 isoform X1

      See identical proteins and their annotated locations for XP_005206521.1

      Conserved Domains (2) summary
      COG0724
      Location:9152
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins
    5. XM_005206465.4XP_005206522.1  cleavage and polyadenylation specificity factor subunit 6 isoform X1

      See identical proteins and their annotated locations for XP_005206522.1

      Conserved Domains (2) summary
      COG0724
      Location:9152
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12643
      Location:82158
      RRM_CFIm68; RNA recognition motif of pre-mRNA cleavage factor Im 68 kDa subunit (CFIm68 or CPSF6) and similar proteins

    RNA

    1. XR_003034616.1 RNA Sequence

    Support Center