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    AOAH acyloxyacyl hydrolase [ Bos taurus (cattle) ]

    Gene ID: 768208, updated on 9-Jan-2020

    Summary

    Official Symbol
    AOAHprovided by VGNC
    Official Full Name
    acyloxyacyl hydrolaseprovided by VGNC
    Primary source
    VGNC:VGNC:25971
    See related
    BGD:BT17544; Ensembl:ENSBTAG00000018119
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See AOAH in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 4 NC_037331.1 (60547452..60732295)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 4 AC_000161.1 (60940605..61125665)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene engulfment and cell motility 1 Neighboring gene uncharacterized LOC104972076 Neighboring gene 40S ribosomal protein S7 pseudogene Neighboring gene anillin actin binding protein Neighboring gene KIAA0895 Neighboring gene endonuclease/exonuclease/phosphatase family domain containing 1

    Genomic regions, transcripts, and products

    General gene information

    Homology

    Clone Names

    • MGC142308

    General protein information

    Preferred Names
    acyloxyacyl hydrolase
    Names
    acyloxyacyl hydrolase (neutrophil)
    NP_001071564.1
    XP_015324869.2
    XP_015324870.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078096.2NP_001071564.1  acyloxyacyl hydrolase precursor

      See identical proteins and their annotated locations for NP_001071564.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123554
      UniProtKB/TrEMBL
      Q08DV1
      Related
      ENSBTAP00000034562.5, ENSBTAT00000034676.5
      Conserved Domains (3) summary
      smart00741
      Location:41114
      SapB; Saposin (B) Domains
      cd01826
      Location:244546
      acyloxyacyl_hydrolase_like; Acyloxyacyl-hydrolase like subfamily of the SGNH-hydrolase family. Acyloxyacyl-hydrolase is a leukocyte-secreted enzyme that deacetylates bacterial lipopolysaccharides.
      pfam03489
      Location:83114
      SapB_2; Saposin-like type B, region 2

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      60547452..60732295
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015469384.2XP_015324870.2  acyloxyacyl hydrolase isoform X2

      Related
      ENSBTAP00000064073.1, ENSBTAT00000082777.1
      Conserved Domains (3) summary
      smart00741
      Location:41114
      SapB; Saposin (B) Domains
      pfam11617
      Location:229257
      Cu-binding_MopE; Putative metal-binding motif
      cl01053
      Location:268499
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
    2. XM_015469383.2XP_015324869.2  acyloxyacyl hydrolase isoform X1

      Conserved Domains (3) summary
      smart00741
      Location:41114
      SapB; Saposin (B) Domains
      cd01826
      Location:268570
      acyloxyacyl_hydrolase_like; Acyloxyacyl-hydrolase like subfamily of the SGNH-hydrolase family. Acyloxyacyl-hydrolase is a leukocyte-secreted enzyme that deacetylates bacterial lipopolysaccharides.
      pfam11617
      Location:229257
      Cu-binding_MopE; Putative metal-binding motif
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