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    ZNF35 zinc finger protein 35 [ Homo sapiens (human) ]

    Gene ID: 7584, updated on 2-Oct-2018

    Summary

    Official Symbol
    ZNF35provided by HGNC
    Official Full Name
    zinc finger protein 35provided by HGNC
    Primary source
    HGNC:HGNC:13099
    See related
    Ensembl:ENSG00000169981 MIM:194533; Vega:OTTHUMG00000133091
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HF10; HF.10; Zfp105
    Expression
    Broad expression in testis (RPKM 5.6), urinary bladder (RPKM 2.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See ZNF35 in Genome Data Viewer
    Location:
    3p21.31
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (44648741..44660791)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (44690108..44702283)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ZNF660-ZNF197 readthrough Neighboring gene ZNF197 antisense RNA 1 Neighboring gene zinc finger protein 197 Neighboring gene zinc finger protein 251 pseudogene Neighboring gene zinc finger protein OZF-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding TAS
    Traceable Author Statement
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific NAS
    Non-traceable Author Statement
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to retinoic acid ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    cell ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein 35
    Names
    zinc finger protein 35 (clone HF.10)
    zinc finger protein HF.10

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_003420.3NP_003411.3  zinc finger protein 35

      See identical proteins and their annotated locations for NP_003411.3

      Status: VALIDATED

      Source sequence(s)
      BC013597, BC015892, BP237260
      Consensus CDS
      CCDS2718.2
      UniProtKB/Swiss-Prot
      P13682
      Related
      ENSP00000379368.2, OTTHUMP00000164121, ENST00000396056.6, OTTHUMT00000256749
      Conserved Domains (4) summary
      COG5048
      Location:214369
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:336356
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:474496
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:488513
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

      Range
      44648741..44660791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p12 PATCHES

    Genomic

    1. NW_009646197.1 Reference GRCh38.p12 PATCHES

      Range
      174095..186145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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