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    Fbxl20 F-box and leucine-rich repeat protein 20 [ Mus musculus (house mouse) ]

    Gene ID: 72194, updated on 9-Sep-2018

    Summary

    Official Symbol
    Fbxl20provided by MGI
    Official Full Name
    F-box and leucine-rich repeat protein 20provided by MGI
    Primary source
    MGI:MGI:1919444
    See related
    Ensembl:ENSMUSG00000020883 Vega:OTTMUSG00000002913
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Scr; Fbl2; C86145; AI849362; AL117906; mKIAA4147; 2610511F20Rik; 4632423N09Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 14.8), thymus adult (RPKM 11.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fbxl20 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (98082554..98150846, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (97943868..98010930, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L19 Neighboring gene SH3 and cysteine rich domain 2 Neighboring gene mediator complex subunit 1 Neighboring gene ribosomal protein S6 pseudogene Neighboring gene predicted gene, 38963 Neighboring gene cyclin-dependent kinase 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA4147

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glutamatergic synapse IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    F-box/LRR-repeat protein 20
    Names
    scrapper

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028149.1NP_082425.1  F-box/LRR-repeat protein 20

      See identical proteins and their annotated locations for NP_082425.1

      Status: VALIDATED

      Source sequence(s)
      AK028535, AK144786, AL591209, BB656518, CX211402
      Consensus CDS
      CCDS25339.1
      UniProtKB/Swiss-Prot
      Q9CZV8
      Related
      ENSMUSP00000099432.3, OTTMUSP00000002821, ENSMUST00000103143.9, OTTMUST00000005970
      Conserved Domains (3) summary
      sd00034
      Location:119144
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:2869
      F-box-like; F-box-like
      cl28166
      Location:220394
      AMN1; Antagonist of mitotic exit network protein 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      98082554..98150846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534298.3XP_006534361.1  F-box/LRR-repeat protein 20 isoform X1

      See identical proteins and their annotated locations for XP_006534361.1

      UniProtKB/Swiss-Prot
      Q9CZV8
      Conserved Domains (3) summary
      sd00034
      Location:121146
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:3071
      F-box-like; F-box-like
      cl28166
      Location:222396
      AMN1; Antagonist of mitotic exit network protein 1
    2. XM_006534299.3XP_006534362.1  F-box/LRR-repeat protein 20 isoform X2

      UniProtKB/Swiss-Prot
      Q9CZV8
      Conserved Domains (3) summary
      cd09293
      Location:206380
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:105130
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:1456
      F-box-like; F-box-like
    3. XM_006534300.1XP_006534363.1  F-box/LRR-repeat protein 20 isoform X3

      Conserved Domains (2) summary
      cd09293
      Location:62236
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:1338
      LRR_AMN1; leucine-rich repeat [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_134030.1: Suppressed sequence

      Description
      NM_134030.1: This RefSeq was permanently suppressed because it is primarily UTR sequence.
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