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    Fbxo9 f-box protein 9 [ Mus musculus (house mouse) ]

    Gene ID: 71538, updated on 5-Aug-2018

    Summary

    Official Symbol
    Fbxo9provided by MGI
    Official Full Name
    f-box protein 9provided by MGI
    Primary source
    MGI:MGI:1918788
    See related
    Ensembl:ENSMUSG00000001366 Vega:OTTMUSG00000034577
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA986398; 9030401P18Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 35.4), adrenal adult (RPKM 26.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fbxo9 in Genome Data Viewer
    Location:
    9; 9 E1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (78081499..78109065, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (77929306..77956860, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene glial cells missing homolog 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene intestinal cell kinase Neighboring gene RNA, 7SK, nuclear

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    fat cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of TOR signaling ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SCF ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081490.2NP_001074959.1  F-box only protein 9 isoform 2

      See identical proteins and their annotated locations for NP_001074959.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 2, which has a longer and distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC159313, AI847242, AK077607, DV657928
      Consensus CDS
      CCDS52864.1
      UniProtKB/Swiss-Prot
      Q8BK06
      Related
      ENSMUSP00000001402.7, OTTMUSP00000047751, ENSMUST00000001402.13, OTTMUST00000087723
      Conserved Domains (2) summary
      pfam12937
      Location:178229
      F-box-like; F-box-like
      cl00299
      Location:82113
      MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
    2. NM_023605.2NP_076094.2  F-box only protein 9 isoform 1

      See identical proteins and their annotated locations for NP_076094.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1.
      Source sequence(s)
      AC159313, AK077607, CX567646
      Consensus CDS
      CCDS52863.1
      UniProtKB/Swiss-Prot
      Q8BK06
      Related
      ENSMUSP00000082419.6, OTTMUSP00000047752, ENSMUST00000085311.12, OTTMUST00000087724
      Conserved Domains (2) summary
      pfam12937
      Location:177228
      F-box-like; F-box-like
      cl00299
      Location:81112
      MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      78081499..78109065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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