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    F2 coagulation factor II, thrombin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712729, updated on 8-Jun-2019

    Summary

    Official Symbol
    F2provided by VGNC
    Official Full Name
    coagulation factor II, thrombinprovided by VGNC
    Primary source
    VGNC:VGNC:72464
    See related
    Ensembl:ENSMMUG00000019674
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    Location:
    chromosome: 14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (19022793..19041862, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (19293593..19312700, complement)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 14 NC_007871.1 (25364059..25398706, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 4 Neighboring gene cytoskeleton associated protein 5 Neighboring gene small nucleolar RNA SNORD67 Neighboring gene uncharacterized LOC114672266 Neighboring gene zinc finger protein 408 Neighboring gene Rho GTPase activating protein 1

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104585.1NP_001098055.1  prothrombin precursor

      See identical proteins and their annotated locations for NP_001098055.1

      Status: PROVISIONAL

      Source sequence(s)
      EF057490
      UniProtKB/TrEMBL
      A0N064
      Related
      ENSMMUP00000025850.3, ENSMMUT00000027637.3
      Conserved Domains (6) summary
      smart00020
      Location:368618
      Tryp_SPc; Trypsin-like serine protease
      smart00069
      Location:3296
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      smart00130
      Location:216298
      KR; Kringle domain
      cd00108
      Location:113194
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00190
      Location:369621
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam09396
      Location:322368
      Thrombin_light; Thrombin light chain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      19022793..19041862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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