Format

Send to:

Choose Destination
    • Showing Current items.

    IYD iodotyrosine deiodinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705471, updated on 29-Apr-2017

    Summary

    Gene symbol
    IYD
    Gene description
    iodotyrosine deiodinase
    See related
    Ensembl:ENSMMUG00000010802
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs

    Genomic context

    See IYD in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    102 current Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (115871640..115905773, complement)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 4 NC_007861.1 (112714084..112742026, complement)

    Chromosome 4 - NC_027896.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain-containing family G member 1 Neighboring gene pleckstrin homology and RhoGEF domain containing G1 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14C Neighboring gene uncharacterized LOC106998080

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Thyroid hormone synthesis, organism-specific biosystem (from KEGG)
      Thyroid hormone synthesis, organism-specific biosystemThyroid hormones triiodothyronine (T3) and thyroxine (T4) are essential for normal development, growth and metabolic homeostasis in all vertebrates, and synthesized in the thyroid gland. The function...
    • Thyroid hormone synthesis, conserved biosystem (from KEGG)
      Thyroid hormone synthesis, conserved biosystemThyroid hormones triiodothyronine (T3) and thyroxine (T4) are essential for normal development, growth and metabolic homeostasis in all vertebrates, and synthesized in the thyroid gland. The function...

    General gene information

    Homology

    General protein information

    Preferred Names
    iodotyrosine dehalogenase 1; iodotyrosine deiodinase 1
    XP_001099028.1
    XP_014992613.1
    XP_014992614.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_8.0.1 Primary Assembly

    Genomic

    1. NC_027896.1 Reference Mmul_8.0.1 Primary Assembly

      Range
      115871640..115905773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137128.1XP_014992614.1  iodotyrosine deiodinase 1 isoform X3

      Conserved Domains (1) summary
      cd02144
      Location:93232
      iodotyrosine_dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.
    2. XM_001099028.3XP_001099028.1  iodotyrosine deiodinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q4F0
      Related
      ENSMMUP00000042914.1, ENSMMUT00000074513.1
      Conserved Domains (1) summary
      cd02144
      Location:93285
      iodotyrosine_dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.
    3. XM_015137127.1XP_014992613.1  iodotyrosine deiodinase 1 isoform X2

      Related
      ENSMMUP00000014152.3, ENSMMUT00000015100.3
      Conserved Domains (1) summary
      cd02144
      Location:93229
      iodotyrosine_dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.
    Support Center