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    MAPKAPK2 MAPK activated protein kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695044, updated on 7-Oct-2019

    Summary

    Official Symbol
    MAPKAPK2provided by VGNC
    Official Full Name
    MAPK activated protein kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:74653
    See related
    Ensembl:ENSMMUG00000023567
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs

    Genomic context

    See MAPKAPK2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (64192388..64241218)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (159881343..159930158, complement)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 1 NC_007858.1 (163629537..163678230, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114680236 Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 3 Neighboring gene 40S ribosomal protein S14 pseudogene Neighboring gene interleukin 10 Neighboring gene interleukin 19

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Neurotrophin signaling pathway, organism-specific biosystem (from KEGG)
      Neurotrophin signaling pathway, organism-specific biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
    • Neurotrophin signaling pathway, conserved biosystem (from KEGG)
      Neurotrophin signaling pathway, conserved biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
    • VEGF signaling pathway, organism-specific biosystem (from KEGG)
      VEGF signaling pathway, organism-specific biosystemThere is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelial cells and it is considered to be a crucial signal transducer in both physiologic and pathologic a...
    • VEGF signaling pathway, conserved biosystem (from KEGG)
      VEGF signaling pathway, conserved biosystemThere is now much evidence that VEGFR-2 is the major mediator of VEGF-driven responses in endothelial cells and it is considered to be a crucial signal transducer in both physiologic and pathologic a...
    • Viral carcinogenesis, organism-specific biosystem (from KEGG)
      Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
    • Viral carcinogenesis, conserved biosystem (from KEGG)
      Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    MAP kinase-activated protein kinase 2
    Names
    mitogen-activated protein kinase-activated protein kinase 2
    XP_001085549.2
    XP_014973486.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      64192388..64241218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015118000.2XP_014973486.1  MAP kinase-activated protein kinase 2 isoform X1

      Conserved Domains (2) summary
      smart00220
      Location:70330
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14170
      Location:63368
      STKc_MAPKAPK2; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 2
    2. XM_001085549.4XP_001085549.2  MAP kinase-activated protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      F7HHY8
      Related
      ENSMMUP00000046259.2, ENSMMUT00000056590.2
      Conserved Domains (2) summary
      smart00220
      Location:70327
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14170
      Location:63365
      STKc_MAPKAPK2; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 2
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