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    Crip1 cysteine rich protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691657, updated on 12-Aug-2018

    Summary

    Official Symbol
    Crip1provided by RGD
    Official Full Name
    cysteine rich protein 1provided by RGD
    Primary source
    RGD:1597237
    See related
    Ensembl:ENSRNOG00000027990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Crip; Crp-1
    Summary
    developmentally regulated LIM motif-containing zinc finger protein that may be involved in Th2 cytokine response [RGD, Feb 2006]
    Expression
    Biased expression in Lung (RPKM 755.9), Thymus (RPKM 591.5) and 8 other tissues See more
    Orthologs

    Genomic context

    See Crip1 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137959171..137967042)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 6 NC_005105.3 (146953514..146961385)

    Chromosome 6 - NC_005105.4Genomic Context describing neighboring genes Neighboring gene metastasis associated 1 Neighboring gene cysteine-rich protein 2 Neighboring gene tubulin epsilon and delta complex 1 Neighboring gene transmembrane protein 121

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    AT DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    AT DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    DNA binding, bending ISO
    Inferred from Sequence Orthology
    more info
     
    DNA binding, bending ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    peptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    peptide binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    zinc ion binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to UV-B ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to UV-B ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cellular response to antibiotic ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to antibiotic ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    immune response ISO
    Inferred from Sequence Orthology
    more info
     
    intrinsic apoptotic signaling pathway in response to DNA damage ISO
    Inferred from Sequence Orthology
    more info
     
    intrinsic apoptotic signaling pathway in response to DNA damage ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    prostate gland stromal morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    response to organic substance ISO
    Inferred from Sequence Orthology
    more info
     
    response to zinc ion ISO
    Inferred from Sequence Orthology
    more info
     
    response to zinc ion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    cysteine-rich protein 1
    Names
    cysteine-rich intestinal protein
    cysteine-rich protein 1 (intestinal)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134933.2NP_001128405.1  cysteine-rich protein 1

      See identical proteins and their annotated locations for NP_001128405.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI716760, CB729209
      UniProtKB/Swiss-Prot
      P63255
      Related
      ENSRNOP00000006835.3, ENSRNOT00000006835.5
      Conserved Domains (1) summary
      cd09478
      Location:457
      LIM_CRIP; The LIM domain of Cysteine-Rich Intestinal Protein (CRIP)
    2. NM_001244867.1NP_001231796.1  cysteine-rich protein 1

      See identical proteins and their annotated locations for NP_001231796.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the predominant transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI716760, FQ223262
      UniProtKB/Swiss-Prot
      P63255
      Conserved Domains (1) summary
      cd09478
      Location:457
      LIM_CRIP; The LIM domain of Cysteine-Rich Intestinal Protein (CRIP)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005105.4 Reference Rnor_6.0 Primary Assembly

      Range
      137959171..137967042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000074.1 Alternate Rn_Celera

      Range
      129765196..129773068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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