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    Gipc1 GIPC PDZ domain containing family, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 67903, updated on 6-Nov-2018

    Summary

    Official Symbol
    Gipc1provided by MGI
    Official Full Name
    GIPC PDZ domain containing family, member 1provided by MGI
    Primary source
    MGI:MGI:1926252
    See related
    Ensembl:ENSMUSG00000019433 Vega:OTTMUSG00000061609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GIPC; TIP-2; TaxIP2; Semcap1; Glut1CIP; Rgs19ip1
    Expression
    Ubiquitous expression in stomach adult (RPKM 41.0), colon adult (RPKM 40.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gipc1 in Genome Data Viewer
    Location:
    8; 8 C2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (83652678..83664789)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (86176577..86188688)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42029 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene DnaJ heat shock protein family (Hsp40) member B1 Neighboring gene prostaglandin E receptor 1 (subtype EP1) Neighboring gene protein kinase N1 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 Neighboring gene adhesion G protein-coupled receptor E5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    actin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    myosin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    brush border ISO
    Inferred from Sequence Orthology
    more info
     
    cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic shaft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendritic spine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    presynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    PDZ domain-containing protein GIPC1
    Names
    GAIP C-terminus-interacting protein
    RGS-GAIP interacting protein GIPC
    RGS-GAIP-interacting protein
    RGS19-interacting protein 1
    SEMCAP-1
    Tax interacting protein, clone 2
    neurophilin1-IP
    regulator of G-protein signaling 19 interacting protein 1
    semaF cytoplasmic domain associated protein
    semaF cytoplasmic domain-associated protein 1
    synectin

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018771.3NP_061241.1  PDZ domain-containing protein GIPC1

      See identical proteins and their annotated locations for NP_061241.1

      Status: PROVISIONAL

      Source sequence(s)
      BC003490
      Consensus CDS
      CCDS22457.1
      UniProtKB/Swiss-Prot
      Q9Z0G0
      Related
      ENSMUSP00000019577.8, OTTMUSP00000077934, ENSMUST00000019577.9, OTTMUST00000150312
      Conserved Domains (1) summary
      cd00992
      Location:132210
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      83652678..83664789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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