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    gmpr2 guanosine monophosphate reductase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 678545, updated on 1-Aug-2018

    Summary

    Official Symbol
    gmpr2provided by ZNC
    Official Full Name
    guanosine monophosphate reductase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1238
    See related
    Ensembl:ENSDARG00000061301 Vega:OTTDARG00000043721
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    wu:fb63f02; zgc:136869

    Genomic context

    See gmpr2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24197457..24204655, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (23926300..23933498, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene leishmanolysin-like peptidase Neighboring gene zgc:153151 Neighboring gene si:ch211-216p19.6 Neighboring gene neural precursor cell expressed, developmentally down-regulated 8 Neighboring gene solute carrier family 7 (amino acid transporter light chain, L system), member 8a

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC136869

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    GMP reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GMP reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    purine nucleobase metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    purine nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    purine ribonucleotide interconversion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    GMP reductase complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GMP reductase 2
    NP_001035394.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040304.1NP_001035394.1  GMP reductase 2

      See identical proteins and their annotated locations for NP_001035394.1

      Status: PROVISIONAL

      Source sequence(s)
      BC115299
      UniProtKB/TrEMBL
      Q1RLT1
      Related
      ENSDARP00000135056.1, OTTDARP00000049641, ENSDART00000167141.3, OTTDART00000063463
      Conserved Domains (2) summary
      PRK05096
      Location:3346
      PRK05096; guanosine 5'-monophosphate oxidoreductase; Provisional
      cd00381
      Location:10336
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24197457..24204655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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