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    Slc13a3 solute carrier family 13 member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64846, updated on 12-Aug-2018

    Summary

    Official Symbol
    Slc13a3provided by RGD
    Official Full Name
    solute carrier family 13 member 3provided by RGD
    Primary source
    RGD:628786
    See related
    Ensembl:ENSRNOG00000019118
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Nadc3
    Summary
    sodium-dependent dicarboxylate transporter involved in transport of di- and tricarboxylates with substrate preference for succinate [RGD, Feb 2006]
    Expression
    Restricted expression toward (RPKM 1513.6) See more
    Orthologs

    Genomic context

    See Slc13a3 in Genome Data Viewer
    Location:
    3q42
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (162084336..162147398, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (168266585..168329647, complement)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene zinc finger protein 334 Neighboring gene zinc finger protein 334 Neighboring gene similar to TP53-regulating kinase (p53-related protein kinase) (Nori-2) Neighboring gene solute carrier family 2 member 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    L-aspartate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    aspartate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    citrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    citrate transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dicarboxylic acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dicarboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    dicarboxylic acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    succinate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    succinate transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 13 member 3
    Names
    Na(+)/dicarboxylate cotransporter 3
    naDC-3
    rNaDC3
    sodium-dependent high-affinity dicarboxylate transporter 2
    sodium-dependent high-affinity dicarboxylate transporter 3
    solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022866.2NP_074057.2  solute carrier family 13 member 3

      See identical proteins and their annotated locations for NP_074057.2

      Status: PROVISIONAL

      Source sequence(s)
      BC129094
      UniProtKB/TrEMBL
      A2VD10
      Related
      ENSRNOP00000025843.4, ENSRNOT00000025843.5
      Conserved Domains (2) summary
      cd01115
      Location:42556
      SLC13_permease; Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is ...
      TIGR00785
      Location:31565
      dass; anion transporter

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      162084336..162147398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      152740642..152803198 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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