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    Cyb5a cytochrome b5 type A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64001, updated on 13-Aug-2019

    Summary

    Official Symbol
    Cyb5aprovided by RGD
    Official Full Name
    cytochrome b5 type Aprovided by RGD
    Primary source
    RGD:620558
    See related
    Ensembl:ENSRNOG00000015205
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cyb5
    Summary
    a heme protein that may act as an electron transporter [RGD, Feb 2006]
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in Liver (RPKM 6092.4), Adrenal (RPKM 2337.7) and 4 other tissues See more
    Orthologs

    Genomic context

    See Cyb5a in Genome Data Viewer
    Location:
    18q12.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (81694818..81726821)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 18 NC_005117.3 (80739215..80770883)

    Chromosome 18 - NC_005117.4Genomic Context describing neighboring genes Neighboring gene similar to preferentially expressed antigen in melanoma like 7 Neighboring gene hypothetical protein LOC100359752 Neighboring gene F-box protein 15 Neighboring gene translocase of inner mitochondrial membrane 21 Neighboring gene polyglutamine-binding protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC108694

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    electron transfer activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    electron transport chain IEA
    Inferred from Electronic Annotation
    more info
     
    response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    cytochrome b5
    Names
    cytochrome b-5
    cytochrome b5 type A (microsomal)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022245.1NP_071581.1  cytochrome b5

      See identical proteins and their annotated locations for NP_071581.1

      Status: PROVISIONAL

      Source sequence(s)
      D13205
      UniProtKB/Swiss-Prot
      P00173
      Related
      ENSRNOP00000020446.3, ENSRNOT00000020446.4
      Conserved Domains (1) summary
      pfam00173
      Location:1184
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005117.4 Reference Rnor_6.0 Primary Assembly

      Range
      81694818..81726821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000086.1 Alternate Rn_Celera

      Range
      76829153..76861638
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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