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    MGRN1 mahogunin ring finger 1 [ Bos taurus (cattle) ]

    Gene ID: 616130, updated on 27-Aug-2018

    Summary

    Gene symbol
    MGRN1
    Gene description
    mahogunin ring finger 1
    See related
    Ensembl:ENSBTAG00000018999
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See MGRN1 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 25 NC_037352.1 (3755136..3791830)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 25 AC_000182.1 (3754919..3791614)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene UBA like domain containing 1 Neighboring gene small nucleolar RNA SNORA1 Neighboring gene uncharacterized LOC112444344 Neighboring gene nudix hydrolase 16 like 1 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 3 Neighboring gene chromosome 25 C16orf71 homolog

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
      Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
      Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

    General gene information

    Homology

    Clone Names

    • MGC139947

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase MGRN1
    NP_001070410.2
    XP_005224604.1
    XP_005224605.1
    XP_005224606.1
    XP_005224607.1
    XP_005224610.1
    XP_024840806.1
    XP_024840807.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076942.2NP_001070410.2  E3 ubiquitin-protein ligase MGRN1

      See identical proteins and their annotated locations for NP_001070410.2

      Status: VALIDATED

      Source sequence(s)
      BC123484, DV815046, DV921089, EE365497
      UniProtKB/TrEMBL
      E1BE47, I6L9J6
      Related
      ENSBTAP00000025290.5, ENSBTAT00000025290.5
      Conserved Domains (2) summary
      cd16789
      Location:277317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl27165
      Location:232331
      PHA02929; N1R/p28-like protein; Provisional

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      3755136..3791830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005224547.4XP_005224604.1  E3 ubiquitin-protein ligase MGRN1 isoform X1

      Conserved Domains (2) summary
      TIGR00599
      Location:273532
      rad18; DNA repair protein rad18
      pfam13920
      Location:274319
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    2. XM_005224549.4XP_005224606.1  E3 ubiquitin-protein ligase MGRN1 isoform X3

      See identical proteins and their annotated locations for XP_005224606.1

      Conserved Domains (2) summary
      TIGR00599
      Location:273532
      rad18; DNA repair protein rad18
      pfam13920
      Location:274319
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    3. XM_005224548.4XP_005224605.1  E3 ubiquitin-protein ligase MGRN1 isoform X2

      Conserved Domains (2) summary
      TIGR00599
      Location:273510
      rad18; DNA repair protein rad18
      pfam13920
      Location:274319
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    4. XM_024985038.1XP_024840806.1  E3 ubiquitin-protein ligase MGRN1 isoform X5

      Conserved Domains (2) summary
      cd16789
      Location:277317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl27165
      Location:232331
      PHA02929; N1R/p28-like protein; Provisional
    5. XM_024985039.1XP_024840807.1  E3 ubiquitin-protein ligase MGRN1 isoform X6

      Conserved Domains (2) summary
      cd16789
      Location:277317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl28410
      Location:273510
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    6. XM_005224553.4XP_005224610.1  E3 ubiquitin-protein ligase MGRN1 isoform X7

      See identical proteins and their annotated locations for XP_005224610.1

      Conserved Domains (2) summary
      cd16789
      Location:277317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl28410
      Location:273500
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    7. XM_005224550.4XP_005224607.1  E3 ubiquitin-protein ligase MGRN1 isoform X4

      Conserved Domains (2) summary
      cd16789
      Location:277317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl28410
      Location:273500
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
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