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    CASQ1 calsequestrin 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 608401, updated on 2-Oct-2018

    Summary

    Official Symbol
    CASQ1provided by VGNC
    Official Full Name
    calsequestrin 1provided by VGNC
    Primary source
    VGNC:VGNC:38738
    See related
    Ensembl:ENSCAFG00000012470
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See CASQ1 in Genome Data Viewer
    Location:
    chromosome: 38
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 38 NC_006620.3 (22012060..22020430, complement)

    Chromosome 38 - NC_006620.3Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 8 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene proliferation and apoptosis adaptor protein 15 Neighboring gene ATPase Na+/K+ transporting subunit alpha 4 Neighboring gene uncharacterized LOC106558361 Neighboring gene immunoglobulin superfamily member 8

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006620.3 Chromosome 38 Reference CanFam3.1 Primary Assembly

    Pathways from BioSystems

    • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
      Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    identical protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    positive regulation of release of sequestered calcium ion into cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of store-operated calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of store-operated calcium entry ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    sarcoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    calsequestrin-1
    Names
    Calsequestrin-1
    calsequestrin, skeletal muscle isoform

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006620.3 Reference CanFam3.1 Primary Assembly

      Range
      22012060..22020430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_845004.3XP_850097.1  calsequestrin-1

      Related
      ENSCAFP00000018363.3, ENSCAFT00000019796.3
      Conserved Domains (1) summary
      cl26077
      Location:31380
      Thioredoxin_6; Thioredoxin-like domain
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