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    EPHA6 EPH receptor A6 [ Canis lupus familiaris (dog) ]

    Gene ID: 607935, updated on 15-Jan-2019

    Summary

    Official Symbol
    EPHA6provided by VGNC
    Official Full Name
    EPH receptor A6provided by VGNC
    Primary source
    VGNC:VGNC:58302
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See EPHA6 in Genome Data Viewer
    Location:
    chromosome: 33
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 33 NC_006615.3 (3990346..4786070)

    Chromosome 33 - NC_006615.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093780 Neighboring gene uncharacterized LOC111093785 Neighboring gene NEDD8-conjugating enzyme UBE2F pseudogene Neighboring gene cell division control protein 42 homolog pseudogene Neighboring gene uncharacterized LOC111093715 Neighboring gene signal recognition particle 9 kDa protein-like Neighboring gene ADP ribosylation factor like GTPase 6 Neighboring gene crystallin beta-gamma domain containing 3 Neighboring gene ribosomal oxygenase 2

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006615.3 Chromosome 33 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    ephrin type-A receptor 6
    XP_013965586.1
    XP_013965587.1
    XP_022269501.1
    XP_022269502.1
    XP_022269503.1
    XP_022269504.1
    XP_022269505.1
    XP_022269506.1
    XP_022269507.1
    XP_022269508.1
    XP_022269509.1
    XP_022269510.1
    XP_022269511.1
    XP_022269512.1
    XP_022269513.1
    XP_022269514.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006615.3 Reference CanFam3.1 Primary Assembly

      Range
      3990346..4786070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014110111.2XP_013965586.1  ephrin type-A receptor 6 isoform X1

      Conserved Domains (8) summary
      cd09547
      Location:9811044
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      smart00454
      Location:9781045
      SAM; Sterile alpha motif
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:622930
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07714
      Location:627926
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    2. XM_022413803.1XP_022269511.1  ephrin type-A receptor 6 isoform X12

      Conserved Domains (6) summary
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:622830
      PKc_like; Protein Kinases, catalytic domain
    3. XM_022413804.1XP_022269512.1  ephrin type-A receptor 6 isoform X13

      Conserved Domains (6) summary
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:622831
      PKc_like; Protein Kinases, catalytic domain
    4. XM_022413805.1XP_022269513.1  ephrin type-A receptor 6 isoform X14

      Conserved Domains (6) summary
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:622833
      PKc_like; Protein Kinases, catalytic domain
    5. XM_022413802.1XP_022269510.1  ephrin type-A receptor 6 isoform X11

      Conserved Domains (6) summary
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:622880
      PKc_like; Protein Kinases, catalytic domain
    6. XM_022413801.1XP_022269509.1  ephrin type-A receptor 6 isoform X10

      Conserved Domains (6) summary
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:622882
      PKc_like; Protein Kinases, catalytic domain
    7. XM_014110112.2XP_013965587.1  ephrin type-A receptor 6 isoform X1

      Conserved Domains (8) summary
      cd09547
      Location:9811044
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      smart00454
      Location:9781045
      SAM; Sterile alpha motif
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:622930
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07714
      Location:627926
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    8. XM_022413795.1XP_022269503.1  ephrin type-A receptor 6 isoform X4

      Conserved Domains (6) summary
      cd09547
      Location:9571020
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:622930
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    9. XM_022413797.1XP_022269505.1  ephrin type-A receptor 6 isoform X6

      Conserved Domains (6) summary
      cd09547
      Location:9391002
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403529
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:622888
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:549622
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    10. XM_022413799.1XP_022269507.1  ephrin type-A receptor 6 isoform X8

      Conserved Domains (6) summary
      cd09547
      Location:922985
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403494
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:587895
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:514587
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    11. XM_022413798.1XP_022269506.1  ephrin type-A receptor 6 isoform X7

      Conserved Domains (6) summary
      cd09547
      Location:929992
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:351477
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:570878
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:241335
      fn3; Fibronectin type III domain
      pfam14575
      Location:497570
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    12. XM_022413800.1XP_022269508.1  ephrin type-A receptor 6 isoform X9

      Conserved Domains (7) summary
      cd09547
      Location:9401003
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:381488
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:581889
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:271365
      fn3; Fibronectin type III domain
      pfam07699
      Location:214250
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:508581
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:1144
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    13. XM_022413793.1XP_022269501.1  ephrin type-A receptor 6 isoform X2

      Conserved Domains (7) summary
      cd09547
      Location:9651028
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403513
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:606914
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam07699
      Location:236272
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam14575
      Location:533606
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    14. XM_022413794.1XP_022269502.1  ephrin type-A receptor 6 isoform X3

      Conserved Domains (6) summary
      cd09547
      Location:9621025
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403510
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:603911
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:530603
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    15. XM_022413796.1XP_022269504.1  ephrin type-A receptor 6 isoform X5

      Conserved Domains (6) summary
      cd09547
      Location:9461009
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403494
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:587895
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:514587
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
    16. XM_022413806.1XP_022269514.1  ephrin type-A receptor 6 isoform X15

      Conserved Domains (6) summary
      cd09547
      Location:904967
      SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
      cd00063
      Location:403494
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:587853
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:293387
      fn3; Fibronectin type III domain
      pfam14575
      Location:514587
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:15166
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors

    RNA

    1. XR_002622192.1 RNA Sequence

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