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    LOC584780 breast cancer 2, early onset [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 584780, updated on 8-Apr-2017

    Summary

    Gene symbol
    LOC584780
    Gene description
    breast cancer 2, early onset
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus
    Also known as
    brca2
    Annotation information
    Annotation category: partial on reference assembly

    Genomic context

    See LOC584780 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    101 current Spur_4.2 (GCF_000002235.4) Unplaced Scaffold NW_011985124.1 (7..39645, complement)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003579738.1 (43266..81278)

    NW_011985124.1Genomic Context describing neighboring genes Neighboring gene toll-like receptor 13

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Fanconi anemia pathway, organism-specific biosystem (from KEGG)
      Fanconi anemia pathway, organism-specific biosystemThe Fanconi anemia pathway is required for the efficient repair of damaged DNA, especially interstrand cross-links (ICLs). DNA ICL is directly recognized by FANCM and associated proteins, that recrui...
    • Fanconi anemia pathway, conserved biosystem (from KEGG)
      Fanconi anemia pathway, conserved biosystemThe Fanconi anemia pathway is required for the efficient repair of damaged DNA, especially interstrand cross-links (ICLs). DNA ICL is directly recognized by FANCM and associated proteins, that recrui...
    • Homologous recombination, organism-specific biosystem (from KEGG)
      Homologous recombination, organism-specific biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
    • Homologous recombination, conserved biosystem (from KEGG)
      Homologous recombination, conserved biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...

    General protein information

    Preferred Names
    breast cancer type 2 susceptibility protein homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_4.2 Primary Assembly

    Genomic

    1. NW_011985124.1 Reference Spur_4.2 Primary Assembly

      Range
      7..39645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011673969.1XP_011672271.1  breast cancer type 2 susceptibility protein homolog

      Conserved Domains (5) summary
      cd04494
      Location:31483406
      BRCA2DBD_OB2; BRCA2DBD_OB2: A subfamily of OB folds corresponding to the second OB fold (OB2) of the 800-amino acid C-terminal ssDNA binding domain (DBD) of BRCA2 (breast cancer susceptibility gene 2) protein, called BRCA2DBD. BRCA2 participates in homologous ...
      pfam00634
      Location:23862415
      BRCA2; BRCA2 repeat
      pfam09103
      Location:30123137
      BRCA-2_OB1; BRCA2, oligonucleotide/oligosaccharide-binding, domain 1
      pfam09169
      Location:28303009
      BRCA-2_helical; BRCA2, helical
      cl09930
      Location:34183491
      RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.
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