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    Prokr1 prokineticin receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 58182, updated on 18-Sep-2018

    Summary

    Official Symbol
    Prokr1provided by MGI
    Official Full Name
    prokineticin receptor 1provided by MGI
    Primary source
    MGI:MGI:1929676
    See related
    Ensembl:ENSMUSG00000049409 Vega:OTTMUSG00000057205
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pkr1; Gpr73; Pk-r1; EG-VEGFR1
    Expression
    Broad expression in genital fat pad adult (RPKM 3.3), liver E14.5 (RPKM 2.0) and 19 other tissues See more
    Orthologs

    Genomic context

    See Prokr1 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (87578589..87590770, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (87528586..87540695, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 10 Neighboring gene Rho GTPase activating protein 25 Neighboring gene predicted gene, 34222 Neighboring gene predicted gene, 34312 Neighboring gene predicted gene, 46964 Neighboring gene aprataxin and PNKP like factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    circadian rhythm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    circadian rhythm TAS
    Traceable Author Statement
    more info
    PubMed 
    coronary vasculature development TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    prokineticin receptor 1
    Names
    G-protein coupled receptor 73

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355655.1NP_001342584.1  prokineticin receptor 1

      Status: VALIDATED

      Source sequence(s)
      AC125171
      Conserved Domains (1) summary
      cd15204
      Location:63353
      7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. NM_021381.4NP_067356.2  prokineticin receptor 1

      See identical proteins and their annotated locations for NP_067356.2

      Status: VALIDATED

      Source sequence(s)
      AC125171, BC059003
      Consensus CDS
      CCDS20323.1
      UniProtKB/Swiss-Prot
      Q9JKL1
      Related
      ENSMUSP00000059034.7, OTTMUSP00000073694, ENSMUST00000050887.8
      Conserved Domains (1) summary
      cd15204
      Location:63353
      7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      87578589..87590770 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506431.3XP_006506494.1  prokineticin receptor 1 isoform X1

      UniProtKB/Swiss-Prot
      Q9JKL1
      Related
      ENSMUSP00000144999.1, OTTMUSP00000073693, ENSMUST00000204682.2, OTTMUST00000140838
      Conserved Domains (1) summary
      cd15204
      Location:63353
      7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. XM_006506433.3XP_006506496.1  prokineticin receptor 1 isoform X2

      Conserved Domains (1) summary
      pfam00001
      Location:1219
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    3. XM_006506432.3XP_006506495.1  prokineticin receptor 1 isoform X1

      See identical proteins and their annotated locations for XP_006506495.1

      UniProtKB/Swiss-Prot
      Q9JKL1
      Conserved Domains (1) summary
      cd15204
      Location:63353
      7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
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