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    pbx2 pre-B-cell leukemia homeobox 2 [ Danio rerio (zebrafish) ]

    Gene ID: 58136, updated on 3-Oct-2019

    Summary

    Official Symbol
    pbx2provided by ZNC
    Official Full Name
    pre-B-cell leukemia homeobox 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000405-5
    See related
    Ensembl:ENSDARG00000019717
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    pbxy; wu:fb73g03

    Genomic context

    See pbx2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (48616220..48643191)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (48674163..48701173)
    103 previous assembly Zv9 (GCF_000002035.4) 16 NC_007127.5 (51950027..51977259)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene exostosin glycosyltransferase 1a Neighboring gene uncharacterized LOC558761 Neighboring gene notch receptor, like Neighboring gene transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    brain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cardiac muscle cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    embryonic retina morphogenesis in camera-type eye IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    heart morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    midbrain development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    skeletal muscle fiber development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pre-B-cell leukemia homeobox 2
    Names
    pre-B-cell leukemia transcription factor 2
    pre-B-cell leukemia transcription factor y

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131612.2NP_571687.1  pre-B-cell leukemia homeobox 2

      See identical proteins and their annotated locations for NP_571687.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01051477, CU694532
      UniProtKB/TrEMBL
      Q9I9B4
      Related
      ENSDARP00000018156.5, ENSDART00000004751.7
      Conserved Domains (2) summary
      cd00086
      Location:253313
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:59251
      PBC; PBC domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      48616220..48643191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017351360.2XP_017206849.1  pre-B-cell leukemia homeobox 2 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IGN9
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