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    runx3 RUNX family transcription factor 3 [ Danio rerio (zebrafish) ]

    Gene ID: 58127, updated on 8-Jun-2019

    Summary

    Official Symbol
    runx3provided by ZNC
    Official Full Name
    RUNX family transcription factor 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000605-2
    See related
    Ensembl:ENSDARG00000052826
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    runxb
    Orthologs

    Genomic context

    See runx3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (45092766..45155284, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (44955862..45018380, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 13 NC_007124.5 (45712363..45775791, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene KH domain containing, RNA binding, signal transduction associated 1a Neighboring gene calcineurin-like EF-hand protein 1 Neighboring gene uncharacterized LOC108191951 Neighboring gene zinc finger-like gene 1g

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chondrocyte differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    embryonic viscerocranium morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hemopoiesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hemopoiesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    runt-related transcription factor 3
    Names
    runt-related transcription factor b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362344.1NP_001349273.1  runt-related transcription factor 3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      CABZ01078998, CABZ01083960, CT025744
      Conserved Domains (2) summary
      pfam00853
      Location:69190
      Runt; Runt domain
      pfam08504
      Location:334438
      RunxI; Runx inhibition domain
    2. NM_131604.3NP_571679.2  runt-related transcription factor 3 isoform 2

      See identical proteins and their annotated locations for NP_571679.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      CABZ01083960, CT025744
      UniProtKB/TrEMBL
      Q9DEA0
      Related
      ENSDARP00000136974.1, ENSDART00000161144.2
      Conserved Domains (2) summary
      pfam00853
      Location:55176
      Runt; Runt domain
      pfam08504
      Location:320424
      RunxI; Runx inhibition domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      45092766..45155284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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