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    six2b SIX homeobox 2b [ Danio rerio (zebrafish) ]

    Gene ID: 566454, updated on 2-Jun-2019

    Summary

    Official Symbol
    six2bprovided by ZNC
    Official Full Name
    SIX homeobox 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080723-23
    See related
    Ensembl:ENSDARG00000054878
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    zgc:195089; zgc:195096

    Genomic context

    See six2b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (25610224..25612007, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (25518864..25520647, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 12 NC_007123.5 (27137876..27139659, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Neighboring gene SIX homeobox 3b Neighboring gene protein kinase C, epsilon a Neighboring gene endothelial PAS domain protein 1a

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    anatomical structure development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    animal organ development IEA
    Inferred from Electronic Annotation
    more info
     
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    SIX homeobox 2b
    Names
    sine oculis-related homeobox 2b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128734.1NP_001122206.1  SIX homeobox 2b

      See identical proteins and their annotated locations for NP_001122206.1

      Status: PROVISIONAL

      Source sequence(s)
      BC163151
      UniProtKB/TrEMBL
      B3DIJ7
      Related
      ENSDARP00000071623.3, ENSDART00000077155.4
      Conserved Domains (2) summary
      cd00086
      Location:129180
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam16878
      Location:9118
      SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      25610224..25612007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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