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    dapk1 death-associated protein kinase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 558314, updated on 12-Aug-2018

    Summary

    Official Symbol
    dapk1provided by ZNC
    Official Full Name
    death-associated protein kinase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-177
    See related
    Ensembl:ENSDARG00000060093 Vega:OTTDARG00000018597
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    wu:fj09c03; si:ch211-66i11.1
    Orthologs

    Genomic context

    See dapk1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (44655124..44795909)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (44054953..44195753)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911103 Neighboring gene growth arrest-specific 1a Neighboring gene cathepsin La Neighboring gene fructose-1,6-bisphosphatase 2

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Autophagy - animal, organism-specific biosystem (from KEGG)
      Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - animal, conserved biosystem (from KEGG)
      Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    death-associated protein kinase 1
    NP_001093460.1
    XP_017211589.1
    XP_017211590.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099990.2NP_001093460.1  death-associated protein kinase 1

      See identical proteins and their annotated locations for NP_001093460.1

      Status: PROVISIONAL

      Source sequence(s)
      BX005015, CT025745
      UniProtKB/TrEMBL
      A5WVL9
      Conserved Domains (7) summary
      smart00220
      Location:13275
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00204
      Location:439564
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08782
      Location:13101399
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      pfam12796
      Location:416508
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:379432
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:412442
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      44655124..44795909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017356101.2XP_017211590.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A5WVL9
      Related
      ENSDARP00000148401.1, ENSDART00000181872.1
      Conserved Domains (7) summary
      smart00220
      Location:13275
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00204
      Location:439564
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08782
      Location:13101399
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      pfam12796
      Location:416508
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:379432
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:412442
      ANK; ANK repeat [structural motif]
    2. XM_017356100.2XP_017211589.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A5WVL9
      Related
      ENSDARP00000105928.2, OTTDARP00000024828, ENSDART00000124059.3
      Conserved Domains (7) summary
      smart00220
      Location:13275
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00204
      Location:439564
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08782
      Location:13101399
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      pfam12796
      Location:416508
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:379432
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:412442
      ANK; ANK repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394606.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      73234..172397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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