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    rhot2 ras homolog family member T2 [ Danio rerio (zebrafish) ]

    Gene ID: 557574, updated on 9-Sep-2018

    Summary

    Official Symbol
    rhot2provided by ZNC
    Official Full Name
    ras homolog family member T2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051120-96
    See related
    Ensembl:ENSDARG00000056328 Vega:OTTDARG00000032124
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    zgc:123249
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    See rhot2 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (37533728..37559128)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (37646008..37671408)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene NLR family, CARD domain containing 3 Neighboring gene clusterin associated protein 1 Neighboring gene WD repeat domain 90 Neighboring gene rhomboid, veinlet-like 1 (Drosophila) Neighboring gene H1 histone family, member 0 Neighboring gene uncharacterized LOC108181544

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC123249

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrial outer membrane permeabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion organization IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion transport along microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial Rho GTPase 2
    Names
    MIRO-2
    ras homolog gene family, member T2
    NP_001032768.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037679.1NP_001032768.1  mitochondrial Rho GTPase 2

      See identical proteins and their annotated locations for NP_001032768.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109430
      UniProtKB/Swiss-Prot
      Q32LU1
      Related
      ENSDARP00000061202.5, OTTDARP00000035442, ENSDART00000061203.6, OTTDART00000044792
      Conserved Domains (5) summary
      smart00174
      Location:7169
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01892
      Location:415591
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:3169
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:341409
      EF_assoc_1; EF hand associated
      pfam08356
      Location:221301
      EF_assoc_2; EF hand associated

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      37533728..37559128
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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