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    C11orf71 chromosome 11 open reading frame 71 [ Homo sapiens (human) ]

    Gene ID: 54494, updated on 11-Jun-2021

    Summary

    Official Symbol
    C11orf71provided by HGNC
    Official Full Name
    chromosome 11 open reading frame 71provided by HGNC
    Primary source
    HGNC:HGNC:25937
    See related
    Ensembl:ENSG00000180425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    URLC7
    Expression
    Broad expression in testis (RPKM 41.5), kidney (RPKM 6.0) and 18 other tissues See more
    Orthologs
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    Genomic context

    See C11orf71 in Genome Data Viewer
    Location:
    11q23.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (114391443..114400511, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (114262165..114271233, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene nicotinamide N-methyltransferase Neighboring gene uncharacterized LOC101928940 Neighboring gene uncharacterized LOC107984391 Neighboring gene RNA binding motif protein 7 Neighboring gene RNA exonuclease 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    Associated conditions

    Description Tests
    Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
    GeneReviews: Not available

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ20010

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in nuclear body IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    uncharacterized protein C11orf71
    Names
    up-regulated in lung cancer 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271562.2NP_001258491.1  uncharacterized protein C11orf71 isoform 1

      See identical proteins and their annotated locations for NP_001258491.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
      Source sequence(s)
      AK000017, AP002373, HY013971
      Consensus CDS
      CCDS76479.1
      UniProtKB/Swiss-Prot
      Q6IPW1
      UniProtKB/TrEMBL
      A0A0A8K8C2
      Related
      ENSP00000492536.1, ENST00000623205.2
      Conserved Domains (1) summary
      pfam15747
      Location:1112
      DUF4687; Domain of unknown function (DUF4687)
    2. NM_019021.4NP_061894.2  uncharacterized protein C11orf71 isoform 2

      See identical proteins and their annotated locations for NP_061894.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon structure in the 3' coding region, and differs in the 3' UTR, compared to variant 1. The encoded isoform (2) is longer and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AP002373, BC071695, HY013971
      Consensus CDS
      CCDS8369.2
      UniProtKB/Swiss-Prot
      Q6IPW1
      Related
      ENSP00000325508.4, ENST00000325636.8
      Conserved Domains (1) summary
      pfam15747
      Location:1112
      DUF4687; Domain of unknown function (DUF4687)

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

      Range
      114391443..114400511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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